Social Anxiety Disorder Clinical Trial
Official title:
CBT Augmentation of Paroxetine for Social Anxiety
This study will determine whether the addition of cognitive behavioral therapy can improve the effectiveness of the medication paroxetine (Paxil®) in treating individuals with social anxiety disorder.
Social anxiety disorder is a prevalent and disabling condition for which effective long-term
treatments need to be identified. Paroxetine is effective in treating the acute symptoms of
social anxiety, but longer-term management remains a challenge. Cognitive behavioral therapy
(CBT) has been effective in treating depression and panic disorder symptoms; it may also be
effective in augmenting paroxetine response and reducing relapse after medication
discontinuation. This study will examine the effects of paroxetine treatment alone and in
combination with CBT.
Participants in this study will receive paroxetine for 12 weeks. After 12 weeks,
participants will be randomly assigned to either add weekly sessions of CBT to their
treatment or to continue taking paroxetine alone for another 16 weeks. After the 16-week
treatment period, participants will have their treatments tapered and will be followed for
an additional 24 weeks. Social anxiety symptoms, rates of remission, and quality of life
will be assessed.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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