Snoring Clinical Trial
Official title:
Mandibular Advancement vs Home Treatment for Primary Snoring: A Randomized Trial (SNORE-LESS)
This is a randomized controlled trial for non-apneic snorers. The primary goal of the study is to evaluate the efficacy of a mandibular advancement device (MAD) vs conservative treatment for adults with non-apneic snoring as measured by the partners report of response to treatment (CGI-I). The secondary goal is to evaluate the effectiveness of treatment of snoring on the Epworth Sleepiness Scale (ESS), a modified Symptoms of Nocturnal Obstruction and Related Events (SNORE-25) questionnaire, the Pittsburgh Sleep Quality Index (PSQI), and the Clinical Global Impression of Severity Scale (CGI-S)
Snoring is a problem which affects roughly half of adults, but rigorous studies on how to treat isolated snoring have not been completed. Mandibular advancement devices (MAD) show consistent improvements in sleep quality for patients with sleep apnea; however, their effect on patients with primary snoring remains less well known. The primary hypothesis proposes that adults with non-apneic snoring treated with a MAD will experience a greater reduction of snoring as measured by the Clinical Global Impression - Improvement (GCI-I) Scale response of the sleeping partner. The plan is to enroll 30 participants and 30 sleeping partner participants for each arm of the trial: 120 participants, or 60 pairs, in total. Participants will use the intervention nightly for a period of 4 weeks after which an end of study visit will occur. All post intervention outcomes will be recorded at the end of the study visit. Knowledge gained from this study will help guide treatment practice and evidence-based approaches regarding non-apneic snoring. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05371509 -
Novel Myofunctional Water Bottle to Reduce OSA and Snoring Study
|
N/A | |
| Active, not recruiting |
NCT02470182 -
Screening for Sleep Disordered Breathing With Minimally Obtrusive Sensors
|
||
| Completed |
NCT03964324 -
NO Measurements in Screening for Asthma and OSA, in Patients With Severe Snoring
|
N/A | |
| Completed |
NCT06186687 -
Rehabilitative Approaches: Myofunctional Therapy and Retropalatal Narrowing and Snoring
|
N/A | |
| Completed |
NCT03333876 -
In Home Assessment of Three Anti-Snoring Devices, a Cross Over Study
|
N/A | |
| Completed |
NCT03640793 -
Prospective Evaluation of a Palato-Pharyngeal Implant System (PPIS) Obstructive Sleep Apnea Syndrome (OSAS)
|
N/A | |
| Not yet recruiting |
NCT04143022 -
Evaluation of the Effects of Acupuncture Press Needle in Mild to Moderate Obstructive Sleep Apnea Patients
|
N/A | |
| Completed |
NCT02834767 -
Genioglossus Muscle Training for Snoring and Obstructive Sleep Apnea
|
N/A | |
| Terminated |
NCT01772017 -
A Trial to Evaluate a Device for the Treatment of OSA and Snoring
|
N/A | |
| Withdrawn |
NCT01680380 -
Tracking Breathing During Sleep With Non-contact Sensors
|
N/A | |
| Unknown status |
NCT00806637 -
Vessel Sealing System Uvulopalatoplasty Versus Uvulopalatal Flap
|
N/A | |
| Completed |
NCT00560859 -
Childhood Adenotonsillectomy Study for Children With OSAS
|
N/A | |
| Terminated |
NCT03701165 -
The Effect of the DryMouth Shield on Snoring
|
N/A | |
| Active, not recruiting |
NCT05643352 -
Barbed Reposition Pharyngoplasty in Patients Complaining of Unilevel Palatal Snoring
|
N/A | |
| Completed |
NCT04086407 -
Apnea Hypopnea Index Severity Versus Head Position During Sleep
|
N/A | |
| Not yet recruiting |
NCT05116657 -
Obstructive Sleep Apnoea Post Covid 19: Role of the Upper Airway Microbiome
|
||
| Completed |
NCT01491828 -
Study to Determine Results of Vibratory Stimulus on Subject's Neck
|
Phase 1 | |
| Completed |
NCT01322334 -
Singing Exercises to Improve Symptoms of Snoring and Sleep Apnea
|
N/A | |
| Terminated |
NCT03316963 -
Neostigmine For Snoring During DISE
|
Early Phase 1 | |
| Completed |
NCT04063917 -
Safety, and Tolerability of the ZENS Device (PLUTO)
|
N/A |