Improving Safety of Antivenom in People Bitten by Snakes

Snake Bites Clinical Trial

Official title:
Low Dose Adrenaline, Promethazine, & Hydrocortisone (Alone and in Combination) to Prevent Acute Adverse Reactions to Antivenom in People Bitten by Snakes: Randomised, Double Blind, Placebo-Controlled Trial

Status Completed

Clinical Trial Summary

A study to increase the safety of polyvalent antivenom involving 1000 patients in three centres: low dose adrenaline, promethazine, & hydrocortisone (alone and in combination) to prevent acute adverse reactions to antivenom in people bitten by snakes: randomised, double blind, placebo-controlled trial.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Snake Bites

Clinical Trial Details

NCT number	NCT00270777
Study type	Interventional
Source	University of Kelaniya
Contact
Status	Completed
Phase	Phase 4
Start date	March 2005
Completion date	April 2008

View Details

See also
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Withdrawn	`NCT02694952` - Non-inferiority Trial of Two Snake Antivenoms in CAR (PAVES)	N/A
Completed	`NCT04520282` - Hemostatic Variables In Snakebite Study
Completed	`NCT01864200` - Randomized, Double-Blind, Placebo-Controlled Study: CroFab® vs Placebo for Copperhead Snake Envenomation	Phase 4
Completed	`NCT04470791` - Cryotherapy as a Coadjuvant in Crotaline Snakebite Management With Antivenom.	N/A