Smoking Clinical Trial
Official title:
Feasibility and Smokers' Reactions to DNA Feedback
The purpose of the study is to explore how feedback of cellular DNA (Deoxyribonucleic Acid) damage, as a marker of exposure to the genotoxic agents of tobacco smoke, promotes cessation.
The study aims to recruit 50 smokers who are not engaged in quitting. The study will involve
two in-person visits. During visit 1, participants will complete a baseline survey and have
their blood drawn. Approximately two weeks later, in visit 2, smokers will be randomized in a
1:2:2 ratio to one of three arms:
1. education about harms of smoking (control group);
2. same education plus information on DNA damage and biomarker feedback (biomarker arm)
without visual of damage; or
3. same as arm 2 except accompanied with visuals of participants' normal and DNA damage
cells. Participants in the this arm will be informed of their proportion of leucocytes
showing DNA damage with pictures of their normal and damaged cells.
The goal of the analyses is to obtain effect size estimates (direction, confidence intervals)
to inform if results align with hypotheses and obtain insights about reactions about the
feedback (Aim 1). The study will collect feasibility data from baseline to three months
(e.g., percentage who show up to the sessions, attrition).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03999411 -
Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients
|
Phase 4 | |
| Completed |
NCT03931772 -
Online Automated Self-Hypnosis Program
|
N/A | |
| Completed |
NCT02649556 -
A 26-week Extension of the ZRHR-ERS-09-US Study Evaluating Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2
|
N/A | |
| Completed |
NCT03901066 -
Smoking Dependence and Periodontitis
|
||
| Recruiting |
NCT05846841 -
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
|
N/A | |
| Completed |
NCT03170752 -
Implementing and Testing a Cardiovascular Assessment Screening Program (CASP)
|
N/A | |
| Completed |
NCT03305978 -
Pulmonary Nodule Detection: Comparison of an Ultra Low Dose vs Standard Scan.
|
N/A | |
| Completed |
NCT00000437 -
Tobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone)
|
Phase 4 | |
| Completed |
NCT06105424 -
BRP1602: Evaluation of Technical and Logistical Feasibility to Measure Lung Permeability
|
N/A | |
| Active, not recruiting |
NCT02752022 -
Monitoring the Transition From Smoking to E-cigarettes
|
||
| Completed |
NCT02901171 -
The Contribution of a Smartphone Application to Acceptance and Commitment Therapy Group Treatment for Smoking Cessation
|
N/A | |
| Completed |
NCT02912000 -
TEACH: Technology Evaluation to Address Child Health
|
N/A | |
| Completed |
NCT03206619 -
A Health Recommeder System to Tailor Message Preferences in a Smoking Cessation Programme
|
||
| Completed |
NCT04340830 -
The Effect of Smoking on Dimensional Changes of Free Gingival Graft Around Dental Implants
|
N/A | |
| Completed |
NCT02949648 -
Electronic Cigarette Use and Quitting in Youth
|
N/A | |
| Completed |
NCT02246114 -
Self-Monitoring of Carbon Monoxide to Enhance Reproductive Outcomes in Women
|
N/A | |
| Completed |
NCT02945371 -
Tailored Inhibitory Control Training to Reverse EA-linked Deficits in Mid-life
|
N/A | |
| Completed |
NCT03448900 -
Intervention Study for Smoking Cessation in Spanish College Students
|
N/A | |
| Completed |
NCT01898507 -
Nicotine Metabolism and Low Nicotine Cigarettes
|
N/A | |
| Completed |
NCT02008292 -
Acetylcholine, Tobacco Smoking, Genes and Nicotinic Receptors
|
N/A |