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Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Electronic Cigarettes vs Combustible Cigarettes and Nicotine Gum

Smoking Clinical Trial

Official title:
A Single-Center, Randomized, Open-Label, Crossover Study to Assess Elements of Abuse Liability for Three Electronic Cigarettes

Clinical Trial Summary

The purpose of this study is to measure plasma nicotine uptake parameters, physiological measures, and subjective effect measures in smokers during and following a single ad libitum use of three electronic cigarettes versus combustible cigarettes and nicotine gum.

Clinical Trial Description

This study will assess various elements that may provide information regarding the potential for electronic cigarettes (e-cigarettes) to be adopted by current smokers. These various elements include: a) nicotine pharmacokinetics (PK), b) physiological measures of pulse rate and blood pressure, and c) subjective effects measured by Urge to Smoke, Product Rating, Intent to Use Product Again, and Product Effects. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02269514
Study type Interventional
Source R.J. Reynolds Vapor Company
Contact
Status Completed
Phase N/A
Start date May 2014
Completion date January 2015
View Details
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