Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch Messaging

Smoking Cessation Clinical Trial

Official title: Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch Messaging

Status Completed

Clinical Trial Summary

The primary purpose of this study is to test the feasibility of sending pre-cessation nicotine patches and to examine the effects associated with the pre-cessation treatment phase. Specifically, this study aims to:

1. See if subjects will use pre-cessation nicotine patches.

2. See if subjects in the pre-cessation nicotine patches go on to get more nicotine patches.

3. See if pre-cessation treatment with nicotine patches leads to a decrease in number of cigarettes smoked per day.

4. See if sending 2-weeks' worth of patches is helpful to the quitting process.

Clinical Trial Description

Quitlines have become central to state tobacco control efforts in the U.S. In addition to offering telephone counseling, many quitlines have begun providing quitting aids (e.g., nicotine patch) to eligible smokers. The nicotine patch has been shown repeatedly to double the rate of quitting success compared to a placebo control. Recently a number of studies have examined the use of patches prior to quitting. A meta-analysis indicates that such pre-cessation treatment with nicotine patches doubles the odds of quitting, compared to starting patch treatment on the quit day, as is traditionally done.

The proposed study would look at both pre-cessation treatment with nicotine patches as well as looking to see if sending clients nicotine patches is helpful in their quitting process. The rationale for pre-cessation treatment with patches is that using patches in this manner would make it easier to quit smoking because it may: reduce the reinforcing effects of cigarette smoking, thus helping to overcome conditioned behavior; reduce the need for inhaled nicotine as smokers naturally decrease their cigarette consumption to titrate the level of nicotine in their system; and/or increase compliance with patch use in the quitting phase.

The rationale for sending nicotine patches is that when callers must go and get the patches on their own it creates a barrier to their quitting so that sending nicotine patches directly to a callers' home would make it easier for them to stay on task and quit. This pilot will allow us to test the feasibility of sending pre-treatment nicotine patches and to examine the effects associated with the pre-cessation treatment phase.

This pilot project has the following specific aims, to examine whether:

1. Subjects will use pre-cessation nicotine patches.

2. Subjects in the pre-cessation nicotine patches go on to get more nicotine patches.

3. Pre-cessation treatment with nicotine patches leads to a decrease in number of cigarettes smoked per day.

4. Sending 2-weeks' worth of patches is helpful to the quitting process.

Results will add to the theoretical understanding of behavior change from which new, effective interventions can spring. ;

Related Conditions & MeSH terms

• Smoking Cessation

• NCT number: NCT01287377
• Study type: Interventional
• Source: University of California, San Diego
• Status: Completed
• Phase: Phase 3
• Start date: November 2010
• Completion date: November 2011