Smoking Cessation Clinical Trial
Official title:
Complementing Current NHS Stop Smoking Service Treatments for Smokers With Behavioural Replacement: The Role of De-nicotinised Cigarettes
The aim of this study is to determine if using a behavioural replacement for smoking
(de-nicotinised cigarettes; DNCs), in addition to standard treatment during the first two
weeks after the target quit date, can reduce urges to smoke over the first 4-weeks of
abstinence. Two hundred smokers who want to quit will be recruited from the community. They
would all receive standard smoking cessation treatment from the NHS Stop Smoking Service
(NHS SSS), which uses a combination of stop smoking medication (e.g. nicotine replacement
therapy, Champix) and motivational support. On their target quit date, participants would be
randomised to receive behavioural replacement ( i.e. use of de-nicotinised cigarettes) plus
standard treatment for the first two weeks of their quit attempt, or to continue with
standard treatment alone. De-nicotinised cigarettes are similar to standard cigarettes
except that they do not deliver nicotine to the smoker. Participants will rate their urges
to smoke at each week. Standard NHS SSS measures will also be taken in addition to user
acceptability ratings and reactions to smoking cues.
The hypothesis is that complementing current NHS SSS treatments with de-nicotinised
cigarettes, to address the non-nicotine factors associated with smoking and to help
extinguish smoking behaviour, would result in lower urges to smoke than standard treatment
alone.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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