Smoking Cessation Clinical Trial
Official title:
Effects of an Extended Period of Varenicline Use Prior to Quitting Smoking on Post-quitting Urges to Smoke
Varenicline (Champix) is a relatively new medicine that is effective in helping people to
quit smoking. It is normally started 1-week before stopping smoking and used for up to 12-24
weeks. We are trying to find out if using varenicline for an extended time (4-weeks) before
stopping smoking is better than the standard 1-week of use prior to stopping.
The study will recruit 100 smokers who want to stop. They will be randomly allocated to
receive varenicline(4−weeks) or placebo (3−weeks followed by 1−week of active treatment as
indicated by standard prescribing practice), followed by a 12−week open label treatment
period where all participants will receive varenicline.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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