Smallpox Clinical Trial
Official title:
A Post Marketing Study of the Safety, Tolerability, and Pharmacokinetics of TPOXX In Adult Subjects Weighing More Than 120 KG
Safety and PK study in adults weighing more than 120 kg
The primary objective of this study is to determine the pharmacokinetic (PK) profile of 600
mg oral TPOXX (3 × 200-mg capsules) administered twice daily (BID) for 7 days in adult
subjects weighing more than 120 kg to determine if a change in dosing regimen would be needed
in these patients.
Secondary:
The secondary objective of this study is to evaluate the safety and tolerability of 600 mg
oral TPOXX administered BID for 7 days in healthy adult subjects weighing more than 120 kg.
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