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A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC

Small Cell Lung Cancer Clinical Trial

Official title:
A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With Relapsed/Refractory Small Cell Lung Cancer

Clinical Trial Summary

A study to evaluate the safety and tolerability of AMG 119 in adult subjects with Relapsed/Refractory Small Cell Lung Cancer (SCLC) and determine the appropriate cell dose.

Clinical Trial Description

This is a phase 1, first-in-human study to evaluate the safety and tolerability of AMG 119, an investigational, Chimeric Antigen Receptor T cell therapy targeting delta-like protein 3 (DLL3) in subjects with relapsed/refractory small cell lung cancer who progressed after at least 1 platinum based chemotherapy regimen. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03392064
Study type Interventional
Source Amgen
Contact
Status Suspended
Phase Phase 1
Start date September 10, 2018
Completion date January 14, 2027
View Details
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