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NCT02995889 Clinical Trial

FLT-PET for Early Detection of Relapse in Patients With Irradiated Lung Cancer

Small Cell Lung Cancer Clinical Trial

Official title:
FLT-PET for Early Detection of Relapse in Patients With Irradiated Lung Cancer

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02995889
Other study ID # 308_14
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date November 2014
Est. completion date February 7, 2020

Study information
Verified date May 2022
Source Rigshospitalet, Denmark
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study investigates the feasibility of FLT-PET to improve the diagnosis of relapse in patients with irradiated lung cancer in comparison with FDG-PET/CT.

Recruitment information / eligibility
Status Completed
Enrollment 64
Est. completion date February 7, 2020
Est. primary completion date February 7, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - history with lung cancer, small cell or non-small cell - radiotherapy of lung cancer ended within the last 24 months - radiotherapy might be normofractionated or stereotactic - current suspicion of relapse - written and oral consent Exclusion Criteria: - communication difficulties - pregnancy or lactation

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• FLT-PET

Locations
Country Name City State
Denmark Dept. of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet Copenhagen
Denmark Dept. Respiratory Medicine, Bispebjerg University Hospital Copenhagen

Sponsors (1)
Lead Sponsor Collaborator
Rigshospitalet, Denmark

Country where clinical trial is conducted

Denmark, 

References & Publications (2)

Christensen TN, Langer SW, Persson G, Larsen KR, Amtoft AG, Keller SH, Kjaer A, Fischer BM. Impact of [(18)F]FDG-PET and [(18)F]FLT-PET-Parameters in Patients with Suspected Relapse of Irradiated Lung Cancer. Diagnostics (Basel). 2021 Feb 11;11(2). pii: 2 — View Citation

Christensen TN, Langer SW, Persson G, Larsen KR, Loft A, Amtoft AG, Berthelsen AK, Johannesen HH, Keller SH, Kjaer A, Fischer BM. (18)F-FLT PET/CT Adds Value to (18)F-FDG PET/CT for Diagnosing Relapse After Definitive Radiotherapy in Patients with Lung Ca — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Number of patients with local and/or regional relapse 6 months
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