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Bronchoscopic Intratumoral Chemotherapy for Small Cell Lung Cancer (SCLC) — SCLC  

Small Cell Lung Cancer Clinical Trial

Official title:
Bronchoscopic Intratumoral Chemotherapy for Small Cell Lung Cancer

Clinical Trial Summary

This project proposes to use bronchoscopic intratumoral chemotherapy for small cell lung cancer in two fashions:

1. to implement a prospective clinical trial to test the feasibility and efficacy of intralesional chemotherapy as consolidative therapy immediately following standard systemic chemotherapy and radiation therapy for patients with limited stage SCLC by comparing tumor growth and survival rates of the treatment group and compare the outcomes to historical controls

2. to implement a prospective clinical trial to test the feasibility and efficacy as measured by tumor growth and survival rates of intralesional chemotherapy for patients with recurrent SCLC after standard treatment.

Clinical Trial Description

Subjects will receive standard of care treatment for SCLC with added treatment of Cisplatin injection via endobronchial ultrasound aided bronchoscopy a total of four times. Outcome measurements of tumor growth and survival will be compared to subjects receiving standard of care treatment only. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01487499
Study type Interventional
Source University of Florida
Contact
Status Terminated
Phase Phase 3
Start date December 2011
Completion date March 2015
View Details
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