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Pembrolizumab in Untreated Extensive SCLC — REACTION  

Small Cell Lung Cancer (SCLC) Clinical Trial

Official title:
REACTION: A Phase II Study of Etoposide and Cis/Carboplatin With or Without Pembrolizumab in Untreated Extensive Small Cell Lung Cancer

Clinical Trial Summary

This is a multicenter, open-label, two armed, controlled, and randomized phase II trial investigating the activity of pembrolizumab in combination with standard chemotherapy in Extensive Disease (ED)-SCLC.

Clinical Trial Description

This is a multicenter, open-label, two armed, controlled, and randomized phase II trial investigating the activity of pembrolizumab in combination with standard chemotherapy in ED-SCLC. Extended stage Small Cell Lung Cancer (SCLC) patients will be registered, after signing the informed consent, and then centrally randomized 1:1 to the experimental arm (Arm A) and the control arm (Arm B). Cross-over at the time of disease progression will be allowed for arm B only. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02580994
Study type Interventional
Source European Organisation for Research and Treatment of Cancer - EORTC
Contact
Status Completed
Phase Phase 2
Start date December 8, 2017
Completion date June 22, 2022
View Details
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