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Clinical Trial Summary

The purpose of this study is learn the effect of gastric bypass surgery and sleeve gastrectomy on glucose metabolism mediated by neural and hormonal factors initiated after eating.


Clinical Trial Description

The purpose of this study is to determine the weight-independent effects of gastric bypass surgery and sleeve gastrectomy surgery on islet cell response after meal ingestion as mediated by hormonal and neural components of the gut. It will also address the differences between the two procedures. Such information will be critical for the development of novel approaches for treatment of diabetes as well as improvement of glycemic effects of gastric bypass and sleeve gastrectomy in patients with partial diabetes remission or relapse after complete remission. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02823665
Study type Interventional
Source The University of Texas Health Science Center at San Antonio
Contact Marzieh Salehi, MD MS
Phone 210-567-6691
Email salehi@uthscsa.edu
Status Recruiting
Phase Early Phase 1
Start date July 2015
Completion date August 2026

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