Effect of Ketone Ester Supplementation on Sleep and Recovery in Hypoxia

Sleep Clinical Trial

Official title: Effect of Ketone Ester Supplementation on Sleep and Recovery in Hypoxia

Status Completed

Clinical Trial Summary

This study specifically aims to elucidate the effects of IEK on sleep and recuperation in hypoxia, after training in normoxia. These conditions are in line with the widely applied live-high train-low strategy. Moreover, blood and tissue oxygenation status, as well as cerebral blood flow and cognitive function will be assessed.

Clinical Trial Description

During training stages in order to prepare for an important event, sleep and recuperation are almost equally important as the appropriate training strategy. This training strategy often consists of living-high (sleeping at -stimulated- altitude) and training low (training at sea level). A decreased oxygen availability, also known as hypoxia, however often disrupts sleep quality and thus compromises the overall training efficiency. Ketones are recently found to improve sleep quality, thus potentially playing a pivotal role in altitude training. Therefore, the investigators want to evaluate the effects of ketones on sleep in hypoxia, after training in normoxia. Moreover, the effect on a performance test, during a simulated 30 min time trial on the next morning, will be investigated. During this protocol, cerebral blood flow will be assessed, as well as ventilation, blood and tissue oxygen status, heart rate variability, and cognitive function. ;

Related Conditions & MeSH terms

• Hypoxia
• Ketosis
• Sleep

• NCT number: NCT06060093
• Study type: Interventional
• Source: KU Leuven
• Status: Completed
• Phase: N/A
• Start date: February 20, 2023
• Completion date: March 31, 2023