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Clinical Trial Summary

This study aims to investigate the effect of a 15-minute meditation practice on sleep architecture and high-frequency Heart Rate Variability (HF-HRV), as well as cognitive performance after both a well-rested and sleep-deprived night.


Clinical Trial Description

Sleep is physiologically important for memory consolidation, mood and hormonal regulation, and maintaining low levels of systemic inflammation. However, a substantial proportion oy f people are reported to regularly sleep less than the recommended 7-9 hours a night. Meditation may be a means to mitigate the negative effects of sleep deprivation, as many types of meditations are associated with increasing high-frequency heart rate variability (HF-HRV), which is an index of parasympathetic control of the heart. Greater parasympathetic drive may be associated with physiological buffering of the detrimental effects of sleep deprivation. The investigators want to conduct a waitlisted randomized control trial where subjects are asked to learn and practice a 15-minute meditation (shoonya meditation) or 15 minutes of alternate nostril breathing, twice a day. Subjects will be asked to complete some cognitive tests before and after a night of sleep and a night of sleep deprivation. During the night of sleep, participants will undergo polysomnography recording for sleep architecture and quality. Subjects will be asked to undergo these same study procedures after 2 months of meditation practice, after which the alternate nostril breathing group will also learn shoonya meditation. Only this group will asked to undergo the same study procedures for a third time, after they have practiced shoonya meditation for 2 months. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05026541
Study type Interventional
Source Beth Israel Deaconess Medical Center
Contact Balachundhar Subramaniam, MD, MPH
Phone 617-667-2721
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date August 2021
Completion date December 2022

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