Sleep Clinical Trial - Effects of Varying Duration of Naps on Cognitive

Status Completed

Clinical Trial Summary

To evaluate the nap duration that achieves maximal cognitive gain with practicality of implementation, the present work employs a within-subject design comparing nap durations of 10 minutes, 30 minutes, and 60 minutes with a no nap condition on benefits to alertness, vigilance, mood, speed of processing and memory over post-nap intervals of 5 minutes, 30 minutes, 60 minutes and 240 minutes. The effect of nap duration on memory encoding will also be examined.

Clinical Trial Description

Naps are a global phenomenon and a commonly adopted lifestyle countermeasure to reduce sleepiness and performance impairments. Experimental studies have also shown that naps can improve cognitive functioning and enhance memory and mood. However, the implementation of naps is highly varied amongst individuals, and it remains uncertain what duration of naps achieves the greatest cognitive benefit. Given the potential for naps to boost productivity in societies such as ours where insufficient nocturnal sleep is prevalent and where work hours are long, an investigation of the optimal nap duration is warranted. Previous studies suggest that the benefits of brief naps (5-15 minutes) occur immediately after the nap and last a limited period (1-3 hours). Longer naps (>30 minutes) are more likely to produce some temporary decrements due to sleep inertia but have the potential to improve cognitive performance for a more sustained period. These findings need to be strengthened through replication and extended to include memory measures that are evaluated over a longer post-nap testing period. To evaluate the nap duration that achieves maximal cognitive gain with practicality of implementation, the present work employs a within-subject design comparing nap durations of 10 minutes, 30 minutes, and 60 minutes with a no nap condition on benefits to alertness, vigilance, mood, speed of processing and memory over post-nap intervals of 5 minutes, 30 minutes, 60 minutes and 240 minutes. The effect of nap duration on memory encoding will also be examined. The investigator's findings are expected to inform theoretical models of sleep and cognition and will aid in the design of practical lifestyle strategies to alleviate sleepiness and improve cognitive performance that may be adopted in an everyday context to boost societal well-being and productivity. ;

Study Design

Related Conditions & MeSH terms

Sleep

Clinical Trial Details

NCT number	NCT04984824
Study type	Interventional
Source	Duke-NUS Graduate Medical School
Contact
Status	Completed
Phase	N/A
Start date	November 1, 2020
Completion date	June 15, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04044495` - Sleep, Rhythms and Risk of Alzheimer's Disease	N/A
Recruiting	`NCT06079853` - Nurse Suicide: Physiologic Sleep Health Promotion Trial	N/A
Completed	`NCT05017974` - Research on Improving Sleep During Pregnancy	N/A
Recruiting	`NCT05206747` - Ottawa Sunglasses at Night for Mania Study	N/A
Enrolling by invitation	`NCT04253054` - Chinese Multi-provincial Cohort Study-Beijing Project
Completed	`NCT04513743` - Ultra Long-Term Sleep Monitoring Using UNEEG™ Medical 24/7 EEG™ SubQ	N/A
Completed	`NCT03251274` - Bath Machine on Sleep Quality in Nursing Home	N/A
Completed	`NCT04102345` - Lavender vs Zolpidem Sleep Quality During Diagnostic PSG	Early Phase 1
Completed	`NCT03725943` - Comparison of Dreem to Clinical PSG for Sleep Monitoring in Healthy Adults	N/A
Active, not recruiting	`NCT05062161` - Sleep Duration and Blood Pressure During Sleep	N/A
Completed	`NCT04562181` - Consistency Evaluation of the qCON, qNOX Indices and Bispectral Index	N/A
Completed	`NCT05102565` - A Dyadic Telehealth Program for Alzheimer's Patients/Caregivers	N/A
Completed	`NCT05576844` - Ai Youmian (Love Better Sleep) for People Living With HIV	N/A
Completed	`NCT04688099` - Synovial Fluid Sleep Study
Recruiting	`NCT04171245` - Prescribing Laughter for Sleep and Wellbeing in UAE University Students	N/A
Completed	`NCT03758768` - The Effects of a Blue Monochromatic Light Intervention on Evening-type Individuals' Sleep and Circadian Rhythms	N/A
Completed	`NCT03163498` - Evaluation of Sleep Pattern and Mood Profile in Hypertensive Patients
Completed	`NCT04093271` - Investigating the Efficacy of Rest-ZZZ Formula in Healthy Participants With Difficulty Falling Asleep or Staying a Sleep	Phase 1
Completed	`NCT03673397` - The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression	N/A
Completed	`NCT04120363` - Trial of Testosterone Undecanoate for Optimizing Performance During Military Operations	Phase 4

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Effects of Varying Duration of Naps on Cognitive Performance and Memory Encoding

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms