Sleep Restriction Clinical Trial
Official title:
The Effect of Short-term Sleep Restriction on Sweet and Fat Taste Preference and Perception.
The study aims is to investigate the effects of sleep restriction on sweet and fat taste perception and preference in both fasted and fed states. This is a randomised crossover trial with sleep restriction (4 hours per night for 2 nights) and normal sleep (at least 8 hours sleep for 2 nights) conditions, with a four-week washout period between conditions.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | February 28, 2023 |
Est. primary completion date | February 28, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - 18 years and above - Self Reported sleep of >7 hours a night Exclusion Criteria: - Dairy allergy - Presence of any serious medical conditions which might influence sleep i.e cardiovascular diseases, diabetes, cancer, respiratory disease, other than mild asthma) - History of bariatric surgery - Taking any kind of medication which might affect regular sleep - Taking any type of medication which might affect appetite - Participating in any kind of dietary and/or weight loss programs - Taking antidepressants - Substance or alcohol abuse - Shift work - Currently having to wake up at night to care for another person - Suffering from and/or receiving treatment for mental health conditions or sleep apnoea. |
Country | Name | City | State |
---|---|---|---|
United Kingdom | University of Glasgow | Glasgow |
Lead Sponsor | Collaborator |
---|---|
University of Glasgow |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Sweet Taste Preference | Preference for sweetness will be assessed by providing participants with 5ml volumes of 5 sucrose solutions with concentrations 3%, 6%, 12%, 24% and 36% in random order. Preference for sweetness will be assessed by asking participants to rate the pleasantness of the solution on a VAS with anchors of 'not at all pleasant' and 'extremely pleasant'.
To determine the preferred optimal sweetness, participants will be presented with pairs of 5 sucrose solutions and asked which solution they prefer. This will continue until the participants consistently choose a preference for a solution twice a row. A maximum of 10 trials will be conducted to assess preference. This assessment will be done fasted and fed state. |
0-4 weeks | |
Primary | Sweet Taste Perception | Perception of sweetness will be assessed by providing participants with 5ml volumes of 5 sucrose solutions with concentrations 3%, 6%, 12%, 24% and 36% in random order. The perception of sweetness will be measured via visual analogue scale (VAS) to rate the sweetness of the solution with anchors of 'not at all sweet' and 'extremely sweet'. | 0-4 weeks | |
Primary | Fat Taste Preference | Preference for fat taste will be assessed by providing participants with 5ml volumes 5 solutions with combinations with concentrations 3%, 6%, 12%, 24% and 36% fat (comprising skimmed milk and double cream mixes of different proportions) in random order. Preference for fat taste will be assessed by asking participants to rate pleasantness of the solution on a VAS with anchors of 'not at all' and 'extremely'.
To determine the preferred optimal fat taste, participants will be presented with 5 pairs of milk and cream mix solutions and asked which solution they prefer. This will continue until the participants consistently choose a preference for one solution twice in a row. A maximum of 10 trials will be conducted to assess preference. This assessment will be done fasted and fed state. |
0-4 weeks | |
Primary | Fat Taste Perception | Perception and preference for fat will be assessed by providing participants with 5ml volumes 5 solutions with combinations with concentrations 3%, 6%, 12%, 24% and 36% fat (comprising skimmed milk and double cream mixes of different proportions) in random order. The perception of fat will be measured via a visual analogue scale (VAS) to rate the creaminess of solution with anchors of 'not at all' and 'extremely'. | 0-4 weeks | |
Secondary | Food preference - explicit liking | Changes in explicit liking measured by the Leeds Food Preference Questionnaire
This assessment will be conducted in a fasted and post-prandial state. Scale range: Changes in explicit liking measured by the Leeds Food Preference Questionnaire. Scoring: The minimum score for VAS scale is 0 and maximum is 100. Scores are recorded and converted in to mean scores for high fat, low fat, sweet or savoury food types and different fat-taste combinations. |
0-4 weeks | |
Secondary | Food preference - explicit wanting | Changes in explicit wanting measured by the Leeds Food Preference Questionnaire
This assessment will be conducted in a fasted and post-prandial state. Scale range: Changes in explicit wanting measured by the Leeds Food Preference Questionnaire. Scoring: The minimum score for VAS scale is 0 and maximum is 100. Scores are recorded and converted in to mean scores for high fat, low fat, sweet or savoury food types and different fat-taste combinations. |
0-4 weeks | |
Secondary | Food reward - implicit wanting | Changes in implicit wanting and food choice measured by the Leeds Food Preference Questionnaire
This assessment will be conducted in a fasted and post-prandial state. Scale range: The computerized asessment where participants are presented with two images and they choose which they like. Scoring: Reaction time for each answer is recorded and converted in to mean scores for high fat, low fat, sweet or savoury food types and different fat-taste combinations. |
0-4 weeks | |
Secondary | Control of Eating Questionnaire - Craving control | Changes in craving control measured by the Control of Eating Questionnaire
This assessment will be conducted in a fasted and post-prandial state. Scale range: The asessment includes a 20 items with a 10 point scale ranging from "not at all" to "extremely" and 1 item with free text answer. Scoring: The minimum score for VAS scale is 0 and maximum is 100. The sum of items were calculated and divided by number of items in the subscale. |
0-4 weeks | |
Secondary | Control of Eating Questionnaire - Craving for sweet | Changes in craving for sweet measured by the Control of Eating Questionnaire
This assessment will be conducted in a fasted and post-prandial state. Scale range: The asessment includes a 20 items with a 10 point scale ranging from "not at all" to "extremely" and 1 item with free text answer. Scoring: The minimum score for VAS scale is 0 and maximum is 100. The sum of items were calculated and divided by number of items in the subscale. |
0-4 weeks | |
Secondary | Control of Eating Questionnaire - Craving for savoury | Changes in craving for savoury measured by the Control of Eating Questionnaire
This assessment will be conducted in a fasted and post-prandial state. Scale range: The asessment includes a 20 items with a 10 point scale ranging from "not at all" to "extremely" and 1 item with free text answer. Scoring: The minimum score for VAS scale is 0 and maximum is 100. The sum of items were calculated and divided by number of items in the subscale. |
0-4 weeks | |
Secondary | Control of Eating Questionnaire - Positive mood | Changes in positive mood measured by the Control of Eating Questionnaire
This assessment will be conducted in a fasted and post-prandial state. Scale range: The asessment includes a 20 items with a 10 point scale ranging from "not at all" to "extremely" and 1 item with free text answer. Scoring: The minimum score for VAS scale is 0 and maximum is 100. The sum of items were calculated and divided by number of items in the subscale. Higher the score indicates higher cravings. |
0-4 weeks |
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