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Sleep Bruxism, Adult clinical trials

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NCT ID: NCT04792398 Not yet recruiting - Clinical trials for Sleep Bruxism, Adult

Bruxism Xeomin® Intervention Trial

BRUX-XIT
Start date: May 1, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to test whether severe masticatory muscle spasms during sleep (e.g. teeth clenching and grinding, known as "bruxism" in technical jargon) demonstrably decrease after application of botulinum toxin type A (Xeomin®). Xeomin® has so far been used to relieve spasms of other muscles and is an approved drug in Switzerland. This study is now intended to test the suitability of this drug for relaxation of the masseter muscle.