Role of Oral Glutathione in Skin Whitening

Skin Whitening Clinical Trial

Official title:

Glutathione as an Oral Whitening Agent: a Randomized, Double-blind, Placebo-controlled Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01016080
• Other study ID #: COA840/2008
• Status: Completed
• Phase: Phase 1
• First received: November 17, 2009
• Last updated: November 17, 2009
• Start date: February 2009
• Est. completion date: June 2009

Study information

• Verified date: November 2009
• Source: Chulalongkorn University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Thailand: Ethical Committee
• Study type: Interventional

Clinical Trial Summary

Oral and intravenous glutathione have been used widely to whiten the skin. The investigators tested this hypothesis by giving oral glutathione for 4 weeks to medical students.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: June 2009
• Est. primary completion date: May 2009
• Gender: Both
• Age group: 18 Years to 25 Years

Eligibility

Inclusion Criteria:

• Healthy medical students

Exclusion Criteria:

• history of skin cancer, especially melanoma

• consumption of any preparations containing glutathione within 1 month of enrollment

• pigmentary disorders or any dermatoses

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Skin Whitening

Intervention

Drug:
• glutathione
250 mg capsules, twice daily, orally
• placebo
250 mg capsules, twice daily, orally

Locations

Country	Name	City	State
Thailand	King Chulalongkorn Memorial Hospital	Bangkok

Sponsors (1)

Lead Sponsor	Collaborator
Chulalongkorn University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Skin melanin index		4 weeks	Yes