Potency of Topical Corticosteroids in Combination Preparations

Status Not yet recruiting

Clinical Trial Summary

Several combination topical drugs are available on the market. The potency of corticosteroids depends on a particular molecular structure and the skin penetration properties. Besides molecular structure, a penetration of a corticosteroid molecule correlates with physical properties of the vehicle which depend on physical properties of the vehicle constituents.

Vasoconstriction assay is considered as the gold standard for testing potency of topical corticosteroids.

Clinical Trial Description

Primary outcome: Change in Vasoconstriction index following application of topical corticosteroids that are incorporated with or without an antibiotic and/or antifungal drugs in healthy volunteers. ;

Study Design

Related Conditions & MeSH terms

Skin Toxicity

Clinical Trial Details

NCT number	NCT03606954
Study type	Interventional
Source	Ben-Gurion University of the Negev
Contact	Raed Khoury, MD
Phone	0507905159
Email	raedkhoury1@hotmail.com
Status	Not yet recruiting
Phase	Phase 4
Start date	November 2018
Completion date	April 2019

View Details

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