Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser for Enlarged Facial Pores

Skin Lesion Clinical Trial

Official title:

Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser in Treatment of Enlarged Facial Pores: A Split-face Comparative Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04470466
• Other study ID #: las49
• Status: Completed
• Phase: N/A
• Start date: July 19, 2020
• Est. completion date: October 12, 2020

Study information

• Verified date: October 2020
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Facial pores are visible topographic features of the skin that reflect openings of pilosebaceous follicles, that may be enlarged causing distress to some individuals. Many patients desire treatment for this condition, which can be an early sign of skin aging. Therapeutic modalities include intense pulsed light, radiofrequency, dermabrasion, oral and topical retinoids, as well as chemical peeling. Lasers, as fractional CO2, short pulse and Q-switched Nd-YAG, can potentially be used in treatment of wide pores. This study aims at the assessment and comparison of therapy with short pulsed and Q-switched Nd-YAG laser plus topical carbon with fractional CO2 laser in the management of wide facial pores.

Description:

topical carbon cream will be applied to one side of the face in patients with wide facial pores, followed by 2 passes of short pulse 1064 ND:YAG laser, then one pass of Q-switched ND-YAG laser. fractional CO2 laser will be performed to the other half of the face. the patients will receive 2 treatment sessions

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: October 12, 2020
• Est. primary completion date: October 12, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Participants who are more than 18 years old with the large facial pores and are aware of their problem and seeking treatment

Exclusion Criteria:

• • Previous laser therapy, chemical peeling, microdermabrasion or cosmetic procedure for the face.
• Patients with any contraindication to laser therapy such as photosensitive diseases, skin malignancies, patients on oral retinoids.
• Keloid-forming tendency.
• Local or systemic treatment for skin pores in the previous 3 months
• Connective tissue disease or the use of immunosuppressive medications.
• Pregnancy.
• Present or past history of herpes labialis.

Related Conditions & MeSH terms

• Skin Lesion

Intervention

Device:
• short pulse and Q-switched ND-YAG laser with topical carbon
application of topical carbon cream, followed by two passes of short pulse 1064 ND-YAG, then one pass of Q-switched 1064 ND-YAG on one side of the face
• fractional CO2 laser
single pass of fractional CO2 laser on the other side of the face

Locations

Country	Name	City	State
Egypt	Kasr Alainy	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the percentage of decrease in size of enlarged facial pores assessed clinically and by dermoscopy		2 months