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Skin Laxity clinical trials

View clinical trials related to Skin Laxity.

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NCT ID: NCT03853980 Active, not recruiting - Skin Laxity Clinical Trials

The INFORM Study: Rotational Fractional Resection for Submental Contouring

Start date: March 18, 2019
Phase: N/A
Study type: Interventional

Efficacy and safety of Rotational Fractional Resection (skin resection) in patients with moderate to severe submental skin laxity.

NCT ID: NCT03534609 Completed - Wrinkle Clinical Trials

Lutronic Genius System for Neck Treatment

Start date: March 27, 2018
Phase: N/A
Study type: Interventional

The Genius system is substantially equivalent to the Infini device (K121481). The study is a prospective, multi-site, non-randomized study of up to 30 treated subjects presenting for treatment of mild to moderate lines, wrinkles, textural concerns, and/or skin laxity of the neck.

NCT ID: NCT03507036 Completed - Skin Laxity Clinical Trials

Radio Frequency Microneedling for Suprapatellar Skin

Start date: March 15, 2018
Phase: N/A
Study type: Interventional

The human skin aging process is characterized by thinning dermis, atrophy of the extracellular matrix, and reduced collagen synthesis. Loss of collagen in the dermis is of aesthetic concern, as it is the main structural support in the dermis and its loss results in skin laxity. Photo-damaged skin, mostly due to UVR, causes degradation of elastic fibers. This is histologically seen as disorganized tangles of elastin. Additionally, as humans age, skin tends to appear more dry due to its poor hydration and turgor capacity. The use of minimally invasive aesthetic treatments in reducing signs of aging has been gaining in popularity over surgical treatments in recent years. Several energy types including, laser, radiofrequency, infrared, and ultrasound, have been developed for facial rejuvenation. These treatments induce controlled thermal damage into the dermis and cause collagen contraction and neocollagenesis resulting in skin tightening over several months. For improving appearance of other anatomical areas, micro-focused ultrasound has been the preferred method, but has shown limited success in tightening the suprapatellar skin. As with facial skin aging, the suprapatellar skin loses elasticity with age and begins to sag. Noninvasive treatments used for the face may also be used in other anatomical areas to produce the same effects of tightening. Minimally invasive bipolar radiofrequency produces a controlled thermal injury in a fractional manner without damaging the dermal-epidermal junction, epidermis or subcutis. Radiofrequency, unlike lasers, are chromophore-independent providing better penetration than lasers, and spare sweat glands, sebaceous glands, and hair follicles.

NCT ID: NCT03407313 Completed - Lipodystrophy Clinical Trials

CONFORM: Rotational Fractional Resection for Submental Contouring

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

This study will evaluate the safety and efficacy of rotational fractional resection (RFR) to improve neck contouring. RFR is used to remove loose skin and fat.

NCT ID: NCT03280069 Recruiting - Clinical trials for Meibomian Gland Dysfunction

Evaluation of Ocular Surface Changes Following RF Electrocoagulation Treatment of the Periorbital Region

Start date: July 25, 2017
Phase: N/A
Study type: Observational

This protocol will evaluate THERMIeyes® for its ability to treat periorbital skin laxity and wrinkles and monitor ocular surface changes and their effect on evaporative dry eye associated with MGD.

NCT ID: NCT02832674 Completed - Skin Laxity Clinical Trials

Safety and Effectiveness Evaluation of the Device in Achieving Submental Lift

Start date: June 25, 2016
Phase: N/A
Study type: Interventional

A prospective evaluation of the ThermiRF device in treating skin laxity under the chin and neck. Seventy male and female subjects between the age of 35 and 65 (inclusive) will be enrolled in this trial. The first 30 subjects will have a total of 6 study visits while the remainder will have a total of 5 study visits. All subjects will have a single treatment administered. The first 30 subjects will have an extra visit at Day 60 intended to allow collection of photo images post treatment to be used for the validation of three blinded raters. Photo images will be collected using 2D standard photography and 3D using the Vectra system. The architecture of the skin in the affected area will be measured using the Cutometer, a suction like instrument that measures elasticity. Sensory and safety will be measured using a 0-10 point numerical rating scale (NRS) and collection of safety reports. The study duration is approximately 6 months.

NCT ID: NCT02770287 Completed - Skin Laxity Clinical Trials

Radiofrequency and Pulsed Electromagnetic Field Treatment of Skin Laxity of the Mon Pubis, Labia and Vaginal Introitus

Start date: March 26, 2016
Phase: N/A
Study type: Interventional

The study will confirm that the Freeze Diamond polar applicator is safe for treating the Mons pubis and Labia, and will result in improvement in general skin appearance including an improvement in skin irregularities and skin laxity.

NCT ID: NCT02763306 Completed - Skin Laxity Clinical Trials

Dermal Cryotherapy in Patients Undergoing Abdominoplasty

Start date: June 2015
Phase: N/A
Study type: Interventional

A prospective, interventional, single-arm study to evaluate histologic changes in skin following cryotherapy with the study device.

NCT ID: NCT02736825 Terminated - Skin Laxity Clinical Trials

Simulines Non-Inferiority Pivotal Study

Start date: April 11, 2016
Phase: N/A
Study type: Interventional

Up to 260 subjects presenting with skin laxity on the face and neck will be randomized to one of two treatment groups. Subjects meeting all entrance criteria will receive study treatment, then complete two post treatment phone contacts and follow-up study visits at 90, 180 and 365 days post treatment. Study images will be obtained pre-treatment, immediately post-treatment, and at each follow-up visit for qualitative and quantitative assessments of efficacy.

NCT ID: NCT02444169 Completed - Skin Laxity Clinical Trials

Retrospective Evaluation of Combination Treatment With the Ulthera System

Start date: April 2015
Phase: N/A
Study type: Observational

A retrospective study to evaluate the Ulthera® System for its potential interaction with toxins and fillers. Up to 500 subjects will be enrolled.