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Skin Health clinical trials

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NCT ID: NCT06452810 Completed - Skin Health Clinical Trials

A Clinical Trial to Evaluate the Effects of a Skin Balm on the Appearance of the Eye Area

Start date: February 29, 2024
Phase: N/A
Study type: Interventional

This virtual single-group clinical trial aims to evaluate the effects of the Sahajan Golden Glow Balm on the health and appearance of the skin in the periorbital area over a period of 6 weeks. Participants will apply the product twice daily and complete questionnaires at various intervals. Photos for expert skin grading will be taken at Baseline and Week 6.

NCT ID: NCT05861622 Completed - Skin Health Clinical Trials

Examining the Efficacy of a Novel Moisturizer Across Eight Weeks

Start date: October 13, 2022
Phase: N/A
Study type: Interventional

Skin moisture is critical to avoid long-term skin damage. Without the necessary moisture, skin is unlikely to have the properties most commonly associated with healthy skin. Recent research has recently highlighted that rambutan extract, niacinamide, and glycoin can all help promote skin moisture and health. To help people experience better skin health, Thu Brulé has developed a serum designed to be used twice daily. Specifically, the test product in this trial was designed to help moisturize the skin and help lock in that moisture. The purpose of this trial is to examine the efficacy of the test product across an eight-week hybrid trial. The outcomes of interest include participants' perceptions of skin health and photographs/images taken of the skin.

NCT ID: NCT04544982 Completed - Skin Health Clinical Trials

Study to Evaluate the Efficacy of Blue Fenugreek Kale Extract (BFKE) on Skin

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Participants will be supplemented BFKE for a period of 8-weeks to improve skin health. The objective of the study is to evaluate the 'Transepidermal Water Loss (TEWL)' that characterizes the skin barrier function of stratum corneum. Additional parameters include, evaluation of skin moisture content, wrinkling, elasticity, sagging, radiance and also on inflammatory biomarkers.

NCT ID: NCT04511052 Completed - Gut Microbiome Clinical Trials

Probiotics for Enhanced Tissue Carotenoid Status in Premenopausal Women

ProCar
Start date: November 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

Carotenoids are yellow-orange fat soluble plant pigments primarily obtained from the diet that serve as an accurate biomarker for fruit and vegetable intake. Carotenoids have demonstrated antioxidant, anti-inflammatory, and anti-obesogenic properties among others. Excess carotenoids are deposited in the skin for storage where they protect against UV skin damage and contribute to improvements in skin health (i.e., decrease the appearance of wrinkles). However, carotenoid status is linked to bioavailability and absorption, which has a high inter-individual variability. It has been hypothesized that inter-individual variations are related to the diversity of gut microbiota. The aim of the present study is to determine whether probiotic supplementation can enhance carotenoid status and responsiveness to carotenoid-mediated changes in blood and skin from intake of a supplement containing mixed forms of carotenoids in pre-menopausal women.

NCT ID: NCT04144777 Completed - Oxidative Stress Clinical Trials

Efficacy of Solarplast for Health and Oxidative Stress

Start date: July 15, 2019
Phase: N/A
Study type: Interventional

Solarplast is a unique mixture of antioxidant enzymes and single antioxidant molecules that are capable of attack oxidants that cause damage to the cells in the human body and cause premature aging. This mechanism may provide protection from stress, such as free radicals, heat, infection, as well as reduce inflammation and participate in the repair mechanism of the intestinal tract. Participants will consume Solarplast, or placebo, for 45 days with blood draws at day-0 and -45 in order to assess antioxidant capacity.

NCT ID: NCT03771807 Completed - Skin Health Clinical Trials

Efficacy of a Nutritional Supplement on Skin Health in Generally Healthy Adults

Start date: January 14, 2020
Phase: N/A
Study type: Interventional

Consumption of dietary supplements has been found to modulate skin health. Individual ingredients such as collagen peptides, lutein and ceramides have been shown to improve skin health. Collagen peptides have been shown to clinically improve skin texture, decrease area of skin ultraviolet damage, increase skin hydration, and improve visible skin results such as hydration, elasticity, wrinkles and roughness. Lutein has been demonstrated to increase skin radiance, protect skin from ultraviolet light, and increase skin hydration. Ceramides derived from wheat have been shown to improve skin texture, increase skin hydration and improve visible skin attributes such as hydration, elasticity, and wrinkles. This study will have subjects consuming a nutritional supplement or placebo daily for 90 days to see if there is an effect on skin health. This study will also have the subjects using a facial cleansing device, which has been shown to improve skin health, on half of their face to determine if there is a synergistic effect between dietary supplement and cleansing device. It is believed, this mixture of collagen peptides, lutein and ceramides has not been studied and the study sponsor hypothesize that this blend of ingredients will have a positive impact on skin health.

NCT ID: NCT03348917 Completed - Skin Health Clinical Trials

The Effect of Skin Cleansers on the Skin Surface Microbiome

Start date: December 28, 2017
Phase: Phase 4
Study type: Interventional

This study determines the effects of a single application of different antiseptic skin cleansers on the composition of the skin surface microbiome using next-generation sequencing (NGS) techniques. Twelve healthy volunteers will receive all three test products in a randomized order to compare the effects of each skin cleanser.

NCT ID: NCT03346447 Completed - Skin Health Clinical Trials

Effect of Baby Wipe Solutions on Fecal Enzyme-induced Irritation

Start date: October 9, 2017
Phase: N/A
Study type: Observational

This is a single-center, prospective, single-blind pilot study to determine baby wipe formulations on an adult dermatitis model.

NCT ID: NCT02525224 Completed - Skin Health Clinical Trials

Nutritional Supplement Efficacy on Cellular Protection and Skin Health in Generally Healthy Adults

Start date: July 2015
Phase: N/A
Study type: Interventional

Healthy skin has been equated with a healthy diet leading to the "inside out" approach to skin health. Since the skin is the barrier to the external world, healthy skin should lead to overall better health. Conversely, the skin derives its nutrition from the internal body requiring the consumption of nutritional supplements for optimal health. This research attempts to examine skin attributes and improved appearance achieved after consumption of a state-of-the-art dietary supplement.

NCT ID: NCT00864188 Completed - Skin Health Clinical Trials

The Influence of Probiotics in a Drinkable Yogurt on Skin Health

Start date: February 2009
Phase: Phase 1
Study type: Interventional

The aim of this study is to test if probiotics administered to healthy female subjects in a dairy format have any skin health benefits.