The Contributions of the Multidisciplinary Management of Prosthesis Knee Infections in a Reference Center: A Retrospective Study About 52 Cases.Skin Coverage in a Reference Center: A Retrospective Study About 52 Cases

Skin Graft Complications Clinical Trial

Official title:

The Contributions of the Multidisciplinary Management of TKA Infections in a Reference Center: A Retrospective Study About 52 Cases.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05367726
• Other study ID #: 776
• Status: Not yet recruiting
• Start date: May 1, 2022
• Est. completion date: September 1, 2022

Study information

• Verified date: May 2022
• Source: Hospices Civils de Lyon
• Contact: Tristan Ferry, Md,PhD
• Phone: 04 26 73 29 38
• Email: tristan.ferry[@]chu-lyon.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Acute and chronic infection of knee joint prosthesis can have several outcomes, the most feared of which is trans-femoral amputation. In order to save the limb while maintaining function, the management of these infections involves several specialists. Orthopedic surgeons are on the front line for carrying out bacteriological samples as well as for changing the material when necessary. The infectiologists coordinate this care by supervising each of the interventions by an antibiotic therapy adapted to the germs and by ensuring the occurrence of adverse events related to the treatment. Plastic surgeons intervene when the skin cover of the knee is deemed to be precarious or when there is an identified loss of substance that could affect the prognosis of the prosthesis. The main objective of our study is to evaluate the success rate of skin coverage and functional recovery for patients cured of their infection. The secondary objective is the identification of risk factors for skin coverage in this population.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 52
• Est. completion date: September 1, 2022
• Est. primary completion date: June 1, 2022
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients with a prosthesis knee infection whose management requires skin covering plastic surgery

• Surgical procedures performed at the Croix Rousse Hospital

Exclusion Criteria:

• none

Related Conditions & MeSH terms

• Communicable Diseases
• Flap Necrosis
• Infections
• Necrosis
• Skin Graft Complications

Intervention

Other:
• patients having had skin coverage of the knee
the cutaneous cover is not always optimal to protect the prosthesis, an act of reconstructive plastic surgery is then necessary

Locations

Country	Name	City	State
France	Hospices Civils de Lyon	Lyon

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	rate of patients with prosthesis knee infection requiring skin coverage	proportion of patients with prosthesis knee infection requiring skin coverage amaong all prosthesis knee infection	2011-2021
Secondary	description of the population at risk of coverage after prosthesis knee infection	rate of failure	2011-2021

External Links

•   website of crioac lyon