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A Human In-vivo Model for the Detection of Inflammatory and Nociceptive Biomarkers

Skin Diseases Clinical Trial

Official title:
Proof-of-concept Study for Bio-marker Assay Validation in Humans

Clinical Trial Summary

This study aims to establish a novel approach assisting the rational development of analgesic and anti-inflammatory drugs. In a first step we will test in healthy human volunteers whether proteins mediating inflammation and pain can be detected in an experimentally induced inflammatory skin lesion. Fluids that will be used to detect such proteins will be collected from the inflamed skin site via small porous catheters. We wish to establish the expression pattern of different proteins and correlate it with various tests assessing pain.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00186563
Study type Interventional
Source Stanford University
Contact
Status Completed
Phase N/A
View Details
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