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Skin Diseases, Infectious clinical trials

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NCT ID: NCT05070754 Completed - Verruca Vulgaris Clinical Trials

Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

Start date: December 2, 2021
Phase: Phase 4
Study type: Interventional

This study is going to test a cold atmospheric plasma device (CAP), in particular a floating electrode-dielectric barrier device (FE-DBD), to treat warts and molluscum. The treatment device in this study generates cold atmospheric plasma (gaseous ionized molecules) to rid the virus from the body. Based on the successes of previous dermatologic studies, FE-DBD is being tested for this study to treat warts and molluscum. Patients will be enrolled to test the efficacy and safety of this device. The duration of the study is 4-12 weeks depending on treatment clearance. The number of lesions will be chosen by the dermatologist. Patients will receive standard of care therapy and/or NTAP depending on the number of lesions.

NCT ID: NCT04781439 Completed - Clinical trials for Skin and Subcutaneous Tissue Infection

The Effect of Early Switching From Intravenous to Oral Antibiotics Therapy

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

To date, many studies showed the great benefits of switching from IV to PO antibiotics in some infectious diseases, especially skin and soft tissue, urinary tract, respiratory tract, gallbladder, and biliary tract infection. Higher level of evidence is necessary to confirm the benefit of early switching protocol in infectious condition management. Therefore, we conducted a clinical trial to investigate the effectiveness and cost of IV-to-PO antibiotic switch therapy in some surgical infection conditions.

NCT ID: NCT04485676 Completed - Clinical trials for Skin Diseases, Infectious

Dalbavancin in Real Clinical Practice in Spain

REAL-DAL
Start date: July 15, 2020
Phase:
Study type: Observational

The aim of this study is to describe the real clinical use of Dalbavancin in Spain between January 2018 and December 2019.

NCT ID: NCT03985475 Not yet recruiting - Skin Infections Clinical Trials

Identification of the Cutaneous Microbiota in Patients With Cutaneous Infection (MICROBIOTA)

Start date: July 1, 2019
Phase:
Study type: Observational [Patient Registry]

Identify the cutaneous microbiota on a cutaneous lesion (cellulite, wound, rash, etc.) on a swab, biopsies or abscess puncture and on "healthy" skin on a skin swab performed for cutaneous mapping to search for staphylococcal deposits.

NCT ID: NCT03981822 Completed - Clinical trials for Sexually Transmitted Diseases

A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital Warts

CARE-1
Start date: June 25, 2019
Phase: Phase 2
Study type: Interventional

This is a Phase 2, double-blind, placebo-controlled study to determine the dose regimen, safety, tolerability, and efficacy of VP-102 in subjects with External Genital Warts (EGW). This study is divided into two parts (Part A and Part B). Increasing durations of skin exposure to study drug (VP-102 or placebo) will be evaluated in three treatment groups prior to progressing to enrollment in Part B. Part A & B will enroll a approximately 108 subjects completing 4 treatment applications every 21 days and continuing with follow-up assessments at Day 84, 112 and 147.

NCT ID: NCT03929224 Completed - Skin Infection Clinical Trials

The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin Breakdown

Start date: October 25, 2018
Phase: Phase 4
Study type: Interventional

Postoperative medicinal grade honey in post-operative care may prevent bone anchored hearing aid associated skin breakdown better than standard care of bacitracin ointment alone in adult patients.

NCT ID: NCT03716024 Completed - Clinical trials for Infectious Skin Disease

Study the Efficacy and Safety of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI)

Start date: July 18, 2007
Phase: Phase 2
Study type: Interventional

A Phase II trial to demonstrate the safety and efficacy of PTK 0796 in the treatment of complicated skin and skin structure infections (cSSSI).

NCT ID: NCT03643952 Completed - Bacteremia Clinical Trials

Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)

Start date: December 6, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety, efficacy and pharmacokinetic (PK) parameters of daptomycin for injection in Japanese pediatric participants aged 1 to 17 years with complicated skin and soft tissue infection (cSSTI) or bacteremia caused by gram-positive cocci.

NCT ID: NCT03637400 Recruiting - Clinical trials for Methicillin-resistant Staphylococcus Aureus

Short and Long Term Outcomes of Doxycycline Versus Trimethoprim-Sulfamethoxazole for Skin and Soft Tissue Infections Treatment

TODOS
Start date: November 26, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare how well two different antibiotics, doxycycline (DOXY) and trimethoprim/sulfamethoxazole (TMP/SMX), work at curing uncomplicated skin and soft tissue infection (uSSTI) such as 1.Boils (pus in the skin, also known as abscesses and furuncles) or 2. Infections that appear only on the skin surface (called cellulitis and erysipelas) that have pus.

NCT ID: NCT03487549 Completed - Virus Diseases Clinical Trials

Cantharidin and Occlusion in Verruca Epithelium

COVE-1
Start date: March 27, 2018
Phase: Phase 2
Study type: Interventional

This is a Phase 2, open label study (Study number VP-102-105; referred to as COVE-1 [Cantharidin and Occlusion in Verruca Epithelium]) to evaluate the efficacy, safety and tolerability of VP-102 treatment in subjects with common warts. This study has two Cohorts.