Efficacy Testing of Melon Oil Olive Pressed Candy Products

Skin Condition Clinical Trial

Official title:

Efficacy Testing of Melon Oil Olive Pressed Candy Products

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05988567
• Other study ID #: 23-049-B
• Status: Completed
• Phase: N/A
• Start date: May 9, 2023
• Est. completion date: December 31, 2023

Study information

• Verified date: February 2024
• Source: TCI Co., Ltd.
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To assess melon and oil olive pressed candy on skin condition improvement

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: December 31, 2023
• Est. primary completion date: June 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Healthy adults aged above 18 years old
• ITA° value 20°-41°

Exclusion Criteria:

• Involuntary subjects.
• Subjects who have a history of skin diseases such as psoriasis, eczema, atopic dermatitis, severe acne; or suffer from other chronic systemic disease.
• Those with known cosmetic, drug or food allergies.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Subjects who have taken oral or topical corticosteroids and other anti-inflammatory drugs in the past 1 month.
• Use of any products or drugs that affect skin color such as fruit acid, salicylic acid (such as Hydroquinone preparations) in the past 2 months.
• In the past 3 months, the test site has used retinoic acid preparations or undergone chemical peeling, laser, pulse light and other medical aesthetic therapists
• Subjects who can not avoid long-term sun exposure

Related Conditions & MeSH terms

• Skin Condition
• Skin Diseases

Intervention

Dietary Supplement:
• Placebo candy
consume 2 tablets per day
• melon and oil olive pressed candy
consume 2 tablets per day

Locations

Country	Name	City	State
Taiwan	Chia Nan University of Pharmacy & Science	Tainan City

Sponsors (1)

Lead Sponsor	Collaborator
TCI Co., Ltd.

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	The change of self-assessment skin and hair condition	A self-assessment questionnaire was collected to evaluate skin and hair condition	Change from Baseline skin and hair condition at 12 weeks
Primary	The change of skin wrinkles	VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units	Change from Baseline skin wrinkles at 12 weeks
Primary	The change of skin texture	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units	Change from Baseline skin texture at 12 weeks
Primary	The change of skin melanin index	Mexameter® MX18 was utilized to measure skin melanin index. Units: arbitrary units	Change from Baseline skin melanin index at 12 weeks
Primary	The change of skin erythema index	Mexameter® MX18 was utilized to measure skin erythema index. Units: arbitrary units	Change from Baseline skin erythema index at 12 weeks
Primary	The change of skin L* value	Chroma Meter MM500 was utilized to measure skin L* value. Units: arbitrary units	Change from Baseline L* value at 12 weeks
Primary	The change of skin b* value	Chroma Meter MM500 was utilized to measure skin b* value. Units: arbitrary units	Change from Baseline b* value at 12 weeks
Primary	The change of skin ITA° value	Chroma Meter MM500 was utilized to measure skin ITA° value. Units: arbitrary units	Change from Baseline ITA° value at 12 weeks
Primary	The change of skin spots	VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units	Change from Baseline skin spots at 12 weeks
Primary	The change of skin UV spots	VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units	Change from Baseline skin UV spots at 12 weeks
Primary	The change of skin brown spots	VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units	Change from Baseline skin brown spots at 12 weeks
Secondary	The change of TEAC of blood	Venous blood was sampled to measure TEAC	Change from Baseline TEAC at 12 weeks
Secondary	The change of SOD of blood	Venous blood was sampled to measure SOD	Change from Baseline SOD at 12 weeks
Secondary	The change of GSH-Px of blood	Venous blood was sampled to measure GSH-Px	Change from Baseline GSH-Px at 12 weeks