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Skin Care clinical trials

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NCT ID: NCT05266209 Completed - Skin Care Clinical Trials

Comparison of Coconut and Sunflower Oil Application in Preserving Babies' Skin Integrity

Start date: March 25, 2022
Phase: N/A
Study type: Interventional

This study was planned to examine the effects of coconut and sunflower oils applied to the skin of newborns on the daily fluid intake and output of the baby, the weight gain/decrease status and skin integrity.

NCT ID: NCT04557371 Completed - Skin Care Clinical Trials

A Study to Assess the Local Cutaneous and Ocular Tolerance of Three Developmental Facial Skin-care Formulations.

Start date: October 12, 2020
Phase: N/A
Study type: Interventional

This study aims to determine the local cutaneous and ocular tolerance of 3 developmental skin-care products; a serum, a lotion, and a cream in healthy female subjects with clinically evaluated sensitive facial skin for 21 days.

NCT ID: NCT04510103 Completed - Skin Care Clinical Trials

A Controlled Clinical Study of 2 Different Moisturizers for the Relief of Dry Skin

Start date: October 23, 2015
Phase: N/A
Study type: Interventional

Dry skin is characterized by a lack of moisture in the outer layer of the skin and can occur as a result of numerous factors including cold weather, low humidity, age, etc. In this study, the moisturizing benefits of two formulas were evaluated for barrier function improvement/impact when used by women with moderately to severely dry skin on their lower legs.

NCT ID: NCT04065035 Completed - Skin Care Clinical Trials

A Clinical Study to Evaluate Efficacy and Tolerability of a Cosmetic Product for Arm Firming

Start date: December 13, 2018
Phase: N/A
Study type: Interventional

This single-center, split-body, double-blind, randomized, controlled clinical trial was conducted to assess the efficacy and tolerance of a topical firming body moisturizer when used over the course of 12 weeks by women with mild to moderate sagging, crepey skin, and overall photodamage on the upper arms. A total of 40 subjects completed study participation which included 10 subjects in the biopsy subgroup.

NCT ID: NCT04007159 Completed - Skin Care Clinical Trials

To Evaluate Skin Irritation and Skin Sensitisation of Developmental Cosmetic Facial Products

Start date: August 30, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to assess irritant or allergic response of 3 developmental cosmetic facial products following a conventional human repeated insult patch test methodology for 6 weeks.

NCT ID: NCT04006795 Completed - Skin Care Clinical Trials

A Photoxicity and Photoallergy Study of a Developmental Face Cream, Serum and Lotion

Start date: August 28, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate the absence of sensitisation and irritation potential of a product when applied to the skin and exposed to ultraviolet (UV) radiation. Photo-sensitisation potential will primarily be evaluated through a subsequent semi-occluded application and UV exposure (challenge phase) after a 2-week rest period. Photo-irritation potential will primarily be evaluated through the repeated occluded application and UV exposure of the study products over 3 weeks (induction phase).

NCT ID: NCT03878381 Completed - Skin Care Clinical Trials

Investigating the Wrinkle Reduction Potential of a Novel Compounded Skin Care Cream

Start date: April 1, 2019
Phase: Early Phase 1
Study type: Interventional

In the realm of cosmetics, skin care accounts for a significant share accounting for 35.3% of the global market, creating a $121 billion industry. While many of the products claim to have unique, natural formulations that boost skin care, many products contain chemicals that are potentially damaging to skin. Such ingredients include preservatives, parabens, fragrances, and formaldehyde, which can cause skin irritation and inflammation. Although these ingredients help to preserve the stability and longevity of products, it is plausible to achieve efficacy and improve skin structure without risking unnecessary damage. The condition and health of the dermis rely largely on elastin, which gives the skin its elasticity, and collagen, which provides structure and strength. Collagen deteriorates naturally with age and exposure to environmental elements such as sunlight and toxins. Many skin rejuvenating interventions have focused on preventing the loss of collagen and elastin. The formulations used in this study will try to optimize cellular physiology, which in turn will create improvement in skin function, collagen strength, and wrinkle depth reduction. The skin care regimen we will be testing includes ingredients such Hyaluronic acid 1%, Vitamin E Acetate, Vitamin A Acetate, Co-enzyme Q 10, L-Arginine, L-glutamine, Phytonadione, Argireline Peptide solution, GABA, Vitamin C, glycolic acid, and Fenugreek. The chemicals used commercially have been avoided in this formulation to enhance the beneficial effects of the product. The purpose of the study is to investigate the efficacy of a new skin care product utilizing the tools of complexion analysis software and optical coherence tomography(OCT). The primary endpoint will be a 15% reduction in facial wrinkles measured by complexion analysis software. Secondary endpoints will be a 10% reduction in skin roughness measured by OCT

NCT ID: NCT03824886 Completed - Pressure Ulcer Clinical Trials

Enhancing SKIN Health and Safety in Aged CARE

SKINCARE
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Aged long-term care receivers are affected by various adverse skin conditions like pressure ulcers, incontinence-associated dermatitis, dryness, intertrigo and many more. Prevention of these skin problems and the provision of general hygiene and skin care activities are key areas of nursing practice. Numerous condition specific guidelines are available and are implemented separately. The more guidelines exist, the more difficult it is for nurses to implement them all. On the other hand, there is a huge overlap in terms of aetiology, pathogenesis and prevention of aforementioned skin conditions. The overall aim of this trial is to test the feasibility and to estimate possible effects of a comprehensive skin care package targeting main nursing relevant skin problems at the same time. Therefore a study will be performed in nursing homes of the state of Berlin comparing the skin care package to standard care. Residents' safety and subjective wellbeing will increase combined with improvements in professional competence of nurses. An advisory board consisting of international experts agreed already to supervise the trial.

NCT ID: NCT03804710 Completed - Skin Care Clinical Trials

To Evaluate the Effect of Moisturizing Creams on Skin Barrier Function

Start date: January 22, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the impact of twice-daily topical application of two different moisturizing creams on skin barrier function for 4 weeks.

NCT ID: NCT03767400 Completed - Skin Care Clinical Trials

Dynamic Optical Coherence Tomography(D-OCT) Aging Study: A Preliminary Evaluation of Structural Differences Between Young and Aged Skin, Cellulite and Atrophic Acne Scars in Female Caucasian Subjects With Fitzpatrick Skin Types I-III Utilizing Non-invasive in Vivo D-OCT.

Start date: December 7, 2018
Phase:
Study type: Observational

This single-center clinical study is being conducted over the course of 2 weeks to conduct an exploratory pilot study as a preliminary evaluation of D-OCT's ability to measure skin changes from aging. Assess structural differences between young and aged skin on the face. To identify the structural characteristics of atrophic acne scars relative to normal skin on the face. To explore characteristics of cellulite relative to normal skin on the thigh in young and aged skin.