Skin Cancer Clinical Trial
Official title:
Impact of Chemical Peels and Fractional Laser on IGF-1 Levels in Skin
The purpose of this study is to evaluate the impact of fractional laser versus chemical peels on IGF-1 levels in skin.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | July 1, 2021 |
Est. primary completion date | July 1, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 55 Years and older |
Eligibility | Inclusion Criteria: - Male and female subjects >55 years old - Fitzpatrick type I-II - Able to provide informed consent. - Cutaneous photodamage of 3 or above on the Larnier photodamage scale (see Appendix). Exclusion Criteria: - Prior laser or peel treatment in the area evaluated in the current study in the past year. - Currently taking immunosuppressant medications known to interfere wound healing or anti-inflammatory medications (such as NSAIDs, or steroids). - Subjects who have underlying diseases that could alter wound healing response (such as Diabetes). - Currently taking insulin. - History of substance abuse, mental dysfunction, or other factors limiting ability to cooperate with study. - History of abnormal scarring such as Keloids. - History of vitiligo. - Allergy or sensitivity or allergy to topical anesthesia - Inability to use sunscreen. - History of smoking in the last 10 years - Scar or prior surgery in the area of treatment. - Use of isotretinoin in the prior 6 months - Subjects who have bleeding disorders or who are taking anticoagulants |
Country | Name | City | State |
---|---|---|---|
United States | Massachusetts General Hospital Clinical Unit for Research Trials and Outcomes in Skin | Boston | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
Massachusetts General Hospital |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | IGF-1 Levels | To quantify IGF-1 levels in skin | 3 months |
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