Skin Aging Clinical Trial
Official title:
Efficacy of Extract of Trigonella Foenum-graceum (Fenugreek) as Topical Phytoestrogen in Skin Aging Treatment of Post Menopausal Women : A Study of COL1A1, COL3A1, Skin Thickness, and Skin Wrinkles
Skin is subjected to intrinsic aging and extrinsic aging. Intrinsic aging is influenced by genetic and hormonal factors. Estrogen has significant role in modulating skin physiology. In post menopausal women, skin aging is accelerated because of hypoestrogenism. Administration of estrogen can delay the process of skin aging. Phytoestrogens are estrogen-like compounds which can be found naturally in plants. The investigators intend to study the efficacy of Trigonella foenum-graceum extract as topical phytoestrogen in skin aging treatment of post menopausal women.
In this double-blinded unmatched randomized controlled trial, the investigators intend to
study the efficacy of Trigonella foenum-graceum extract as topical phytoestrogen in skin
aging treatment of post menopausal women. The investigators have gathered 21 participants
that will be divided into 2 groups, experimental group and control group. Experimental group
will get treatment with topical cream containing Trigonella foenum-graceum extract, while
control group will get treatment with placebo cream.
The study will be held in esthetic cluster, Kencana Cipto Mangunkusumo Hospital, and
radiology cluster, Kencana Cipto Mangunkusumo Hospital from August 2019 until November 2019.
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