Fractional Co2 Laser Versus Microbotox Injection in the Treatment of Wide Facial Pores: A Split Face Comparative Study

Skin Abnormalities Clinical Trial

Official title: Fractional Carbon Dioxide Laser Versus Microbotox Injection in the Treatment of Wide Facial Pores: A Split Face Comparative Study

Status Not yet recruiting

Clinical Trial Summary

1. Evaluation of fractional Co2 laser as a treatment option for wide pores in skin type (III - VI)

2. Evaluation of mesobotox as a new modality for improving wide pores appearance.

3. Comparison of both treatment modalities in treatment of enlarged pores.

Clinical Trial Description

Skin pores (SP), as they are called by laymen, are common and benign features mostly located on the face (nose, cheeks, etc) that generate many aesthetic concerns or complaints.

Enlarged skin pores refer to conditions that present with visible topographic changes of skin surfaces. Although not a medical concern, enlarged pores are a cosmetic concern for a large number of individuals.

Enlarged facial pores affect individuals of different ages, sexes, and races for which many seek treatment. The exact patho-mechanism of enlarged facial pores is not completely understood. Possible causes include genetic predisposition, seborrhea, aging, increased ultraviolet exposure and comedogenic products.

The treatment of dilated facial pores is difficult, and the ideal modality is not established yet. Many treatment modalities reduce facial pores' count and area, including oral and topical medications as well as different wavelengths of laser. Different ablative and non ablative lasers have been used in the treatment of dilated pores with variable outcomes.

The short-term results showed that treatment with low energy level CO2 fractional laser therapy could be a safe and effective option for patients with Fitzpatrick skin Types III and IV who are concerned with enlarged pores.

Microbotox also called mesobotox, is the injection of multiple microdroplets of diluted onabotulinum toxin A into the upper dermis. It has been previously used in study to decrease pore size and to improve skin texture.

Microbotox has been proved to be effective in improving the sheen and texture of the skin, as well as decreasing sweat and sebum production and enlarged pores as it causes atrophy of sebaceous glands, which subsequently causes tightening of the skin envelope. ;

Related Conditions & MeSH terms

• Skin Abnormalities

• NCT number: NCT05923996
• Study type: Interventional
• Source: Assiut University
• Contact: Ahmed AE Ibrahim
• Phone: 01200889665
• Email: ahmedalaa12494@gmail.com
• Status: Not yet recruiting
• Phase: Phase 1
• Start date: February 1, 2024
• Completion date: August 1, 2024