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The Role of Ninjurin-1 During Systemic Inflammation — Ninj1  

SIRS Clinical Trial

Official title:
Prospective Study to Analyze Ninjurin-1 and Its Soluble Part During Systemic Inflammation

Clinical Trial Summary

- With the underlying study the investigators address the question if Ninjurin-1 (Ninj1) expression is altered in patients with systemic inflammatory response syndrome (SIRS) in comparison to healthy volunteers.

- The adhesion molecule Ninj1 is induced following nerve injury where it contributes to nerve generation. Besides it is described to facilitate leukocyte migration especially in the nervous system.

- The investigators hypothesize that Ninj1 expression is increased in SIRS patients, which will fortify its impact during inflammation and the transferability from bench to bedside.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02079597
Study type Observational
Source Johann Wolfgang Goethe University Hospitals
Contact
Status Completed
Phase N/A
Start date February 2014
Completion date September 2014
View Details
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