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NCT05301777 Clinical Trial

Computed Tomography Anatomy of the Paranasal Sinuses and Anatomical Variants of Clinical Relevants in Egyptian Adults .

Sinusitis Clinical Trial

Official title:
Computed Tomography Anatomy of the Paranasal Sinuses and Anatomical Variants of Clinical Relevants in Egyptian Adults .

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05301777
Other study ID # CT paranasal sinuses
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date April 1, 2022
Est. completion date June 1, 2023

Study information
Verified date March 2022
Source Assiut University
Contact Aya Moghazy
Phone 01030361057
Email eaya598@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aim of this study is to show the anatomy of the paranasal sinuses as delineated by the computed tomography among egyptian adults and to describe the variants which not only predispose to chronic sinusitis but may lead to complications in endoscopic sinonasal surgery.

Description:

The paranasal sinuses are group of air filled spaces surrounding the nasal cavity; which start developing from the primitive choana at 25-28 weeks of gestation.1 Three projections arise from the lateral wall of the nose and serve as the beginning of the development of the paranasal sinuses. The anterior projection forms the Aggernasi, the inferior or maxiloturbinate projection forms the inferior turbinates and maxillary sinus, while the superior or ethmoidoturbinate projection forms the ethmoidal air cells and their corresponding drainage channels. The sinuses are named from the facial bones in which they are located. The maxillary and ethmoid sinuses are aerated at birth, while the sphenoid sinuses and frontal sinuses are pneumatized at about the 2nd and 6th year of life respectively.1 The sinuses reach the adult size at adolescent age.1 Radiologic evaluation of the paranasal sinuses is essential in delineating the location and extent of sinonasal diseases and in planning surgical intervention. Plain radiography, computed tomography and magnetic resonance imaging are applied in evaluating the sinuses. Standard paranasal sinus radiograph can readily demonstrate the maxillary or frontal sinus diseases but incompletely delineates ethmoid sinus due to overlapping of structures.2 The role of Magnetic resonance imaging is limited but may provide information on paranasal sinuses fungal infection and differentiating thickened mucosa from fluid retention. Computed tomography is considered the method of choice in delineating completely the normal anatomy and anatomical variants of the paranasal sinuses and it is extremely useful in the pre-operative planning and in post operative follow-up in cases of endonasal interventions. The development of the paranasal sinuses especially the ethmoid labyrinth is associated with anatomical variations.3 Some of which are common while others are rare. Recognition of these variants is important to both the rhinologist and radiologist. Proximity of these occasional cells to the main drainage pathway of the paranasal sinuses may reduce the mucociliary clearance, thus predisposing to inflammatory processes and causing endonasal endoscopic surgery complications.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 200
Est. completion date June 1, 2023
Est. primary completion date April 1, 2023
Accepts healthy volunteers
Gender All
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria: - all cases of computed tomography scan of the paranasal sinuses obtained in the Radiology department of our health institution Exclusion Criteria: - Patients with facial trauma, positive paranasal sinus pathology, head and neck tumours and previous surgery were excluded.

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Computed tomography
Computed tomography

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Outcome
Type Measure Description Time frame Safety issue
Primary show the anatomy of the paranasal sinuses as delineated by the computedtomography and show the anatomy of the paranasal sinuses as delineated by the computedtomography and to describe the variants which not only predispose to chronic sinusitis but may lead to complications in endoscopic sinonasal surgery. Baseline
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