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NCT02071667 Clinical Trial

Association of Periostin Levels and Chronic Sinusitis

Sinusitis Clinical Trial

Official title:
Association of Periostin Levels and Chronic Sinusitis

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT02071667
Other study ID # 17123
Secondary ID
Status Withdrawn
Phase N/A
First received February 20, 2014
Last updated May 1, 2017
Start date September 2014
Est. completion date October 2016

Study information
Verified date May 2017
Source University of Virginia
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to see if a protein in blood, called periostin, can determine if patients have chronic sinusitis. This protein is in everyone's body, but the level of the protein may indicate certain conditions such as chronic sinusitis. The investigators are interested in testing levels of periostin to see if they are higher or lower than patients without chronic sinusitis, just as periostin is higher in patients with asthma. All patients enrolled in this study will have chronic sinusitis without asthma.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date October 2016
Est. primary completion date September 2016
Accepts healthy volunteers No
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria:

- Patients with sinus disease which requires surgical intervention

- Ability to understand and give informed consent

Exclusion Criteria:

- Previous diagnosis of asthma

- Positive methacholine challenge at screening

- Diagnosis of cystic fibrosis

- Concomitant use of systemic corticosteroids (except for those prescribed as part of standard pre-surgical treatment)

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Blood draw

Locations
Country Name City State
United States University of Virginia Charlottesville Virginia

Sponsors (1)
Lead Sponsor Collaborator
University of Virginia

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Difference in circulating serum periostin levels pre and post sinus surgery Serum collected prior to and following sinus surgery will be analyzed for concentrations of the protein periostin. 10-15 weeks
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