Evaluation of Fontan-Associated Liver Disease — FALD  

Single Ventricle Heart Disease Clinical Trial

Official title: Imaging and Biomarker Evaluation of Hepatic Stiffness in Children Enrolled in the Fontan Udenafil Exercise Longitudinal Study

Status Active, not recruiting

Clinical Trial Summary

A study to evaluate the efficacy of MZ101 therapy in reducing liver stiffness.

Clinical Trial Description

This is open-label, long-term prospective study in a cohort of Fontan subjects taking drug daily for one year. The study will determine the scope of hepatic stiffness in the cohort by ultrasound and magnetic resonance imaging elastography and evaluate MZ101 pharmacotherapy as a potentially efficacious treatment to reduce liver stiffness. ;

Related Conditions & MeSH terms

• Heart Diseases
• Single Ventricle Heart Disease

• NCT number: NCT03430583
• Study type: Observational
• Source: Mezzion Pharma Co. Ltd
• Status: Active, not recruiting
• Start date: February 20, 2018
• Completion date: August 31, 2021