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Clinical Trial Summary

Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.


Clinical Trial Description

Simple renal cysts (SRC) are the most frequent type of cystic renal disease. The prevalence rate of SRCs is about 10% and increases with age. Hypertension and decreased renal functions have been reported to occur more commonly among these patients with SRC and there are no clear guidelines for managing asymptomatic SRCs.Renal functional reserve (RFR) describes the capacity of the intact nephron mass to increase glomerular filtration rate(GFR) from baseline in response to stimuli (e.g., protein load).The investigators hypothesized that RFR may be improved in some patients with simple renal cysts after laparoscopic deroofing despite identical resting glomerular filtration rate (rGFR).The aim of this study is to examine whether there is improvement of RFR in patients with simple renal cysts after laparoscopic deroofing. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03259594
Study type Interventional
Source Xuanwu Hospital, Beijing
Contact Zhenhua Shang, MD.
Phone +8617801117318
Email shangzhenhua16@126.com
Status Recruiting
Phase N/A
Start date March 1, 2018
Completion date December 31, 2021

See also
  Status Clinical Trial Phase
Not yet recruiting NCT05134077 - Influence of Simple Renal Cysts on Renal Function N/A