Silicosis Clinical Trial
Official title:
Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma
NCT number | NCT04205708 |
Other study ID # | 10140 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | January 14, 2019 |
Est. completion date | June 10, 2022 |
Verified date | December 2023 |
Source | University of Oklahoma |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Silicosis, a preventable yet irreversible occupational lung disease, has an insidious onset with a latency period for diagnosis extending beyond 10 years from the initial exposure. The central hypothesis of this study is that silicosis cases may currently be going undetected. The long-term goal of this research is to determine the current prevalence and forecast the future prevalence of silicosis and other pneumoconiosis among working populations in Oklahoma and to assist the public health and the healthcare system in planning for a potential resurgence of silicosis.
Status | Completed |
Enrollment | 183 |
Est. completion date | June 10, 2022 |
Est. primary completion date | February 24, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 30 Years and older |
Eligibility | Inclusion Criteria: - Male 30 years or older - Past or present employment in dusty environment, exposed to dust at work - Ability to consent and answer the questionnaire Exclusion Criteria: - Female - Never exposed to dusty environment or never exposed to dust at work - Inability to consent and answer the questionnaire - Age 29 years or younger |
Country | Name | City | State |
---|---|---|---|
United States | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma |
Lead Sponsor | Collaborator |
---|---|
University of Oklahoma |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Estimate of average cumulative respirable crystalline silica exposure (semi-quantitative) | Estimate of average cumulative respirable crystalline silica exposure (semi-quantitative) | Single point assessment at baseline survey | |
Primary | Percentage of participants who report any exposure to silica | Percentage of participants who report any exposure to silica | Single point assessment at baseline survey | |
Primary | Prevalence of silicosis among study group | Percentage of participants with confirmed diagnosis of silicosis | Single point assessment at clinic visit | |
Secondary | Analysis to determine if any demographic, work history, or other trait correlates with increased silica exposure | Analysis to determine if any demographic, work history, or other trait correlates with increased silica exposure | Single point assessment at baseline survey |
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