Silent; Thrombosis Clinical Trial
Official title:
Detection of Asymptomatic Venous Thrombosis in Gynecological Patients With Pelvic Masses
Venous thromboembolism (VTE) is a serious preventable complication of gynecological surgery. High incidence of silent VTE before surgery seems attributable to the high incidence of VTE after surgery in ovarian cancer .so the aim of work is to detect silent venous thrombosis in gynecological patients suffering from pelvic masses using different imaging modalities .
High incidence of silent VTE before surgery seems attributable to the high incidence of VTE
after surgery in ovarian cancer .
The incidence rate of DVT is about 10% to 40% in medical or general surgical patients without
prophylaxis .With prophylaxis, the postoperative incidence of VTE was 1.14% in women with
gynecological disease, and 0.7% in patients undergoing laparoscopic gynecological surgery,
0.3% in patients undergoing urogynecological surgery, and 4% in gynecological cancer
patients, respectively. Most of published studies enrolled only symptomatic patients with
DVT, whereas asymptomatic patients could be easily neglected under the absence of effective
detection. In fact, approximately 50% of DVT patients are silent, so the actual incidence of
postoperative DVT might be higher than reported . The asymptomatic DVT has been confirmed to
increase the development of post-thrombotic syndrome (PTS).
The essence of any surveillance strategy would be the identification of DVT in the
expectation that anticoagulation at the presymptomatic stage would prevent fatal pulmonary
embolism .
A number of imaging modalities are currently available to evaluate deep venous system in a
comprehensive manner allowing correct assessment of presence of thrombosis . Color Doppler
ultrasound has become the primary non invasive diagnostic method for DVT.
All patients are going to be examined by color Doppler ultrasound and by direct MDCT
venography .
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