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Sickle Cell Retinopathy clinical trials

View clinical trials related to Sickle Cell Retinopathy.

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NCT ID: NCT06396403 Recruiting - Sickle Cell Disease Clinical Trials

The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy

RAVOS
Start date: June 13, 2023
Phase:
Study type: Observational

Objective: to gain insight in the pathogenesis, to identify biomarkers to recognize patients at risk for proliferative SCR and to investigate its associations with clinical and laboratory characteristics. Endpoints: The investigators will determine the difference in the above named parameters between patients with and without PSCR Study design: This case control study will include adult sickle cell disease patients with the HbSS or HbSC genotype. For both genotypes, 20 patients without sickle cell retinopathy (SCR) and 20 patients with PSCR will be included, resulting in a total of 80 patients. Venous blood samples and retinal imaging scans will be collected for each included patient.

NCT ID: NCT03068702 Completed - Clinical trials for Sickle Cell Retinopathy

New, Previously Unknown, Uses of Optical Coherence Tomography Angiography (OCTA)

OCTA
Start date: August 21, 2016
Phase: N/A
Study type: Observational

Sickle cell maculopathy was sparingly mentioned in the literature before despite the fact that sickle cell disease or sickle cell trait is common in people of many areas of the world. This study shows that OCTA is a very valuable, non invasive, office procedure that may well be used in diagnosing this disease.