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Sickle Cell Improvement: Enhancing Care in the Emergency Department — SCIENCE  

Sickle Cell Crisis Clinical Trial

Official title:
Sickle Cell Improvement: Enhancing Care in the Emergency Department

Clinical Trial Summary

Sickle cell disease (SCD) is an inherited blood disorder affecting approximately 36,000 children in the United States, approximately 90% of whom are Black. The disease is characterized by recurrent, severe pain crises which result in high rates of emergency department visits and hospitalizations, and decreased quality of life. The National Heart, Lung and Blood Institute, as well as the American Society of Hematology, have endorsed pain management guidelines regarding the timeliness of care for children presenting with these acute pain crises. These evidence-based guidelines are infrequently followed, resulting in increased pain and hospitalizations. In additional to other barriers to following the guideline, structural racism has been proposed as a significant contributor and the New England Journal of Medicine recently called for the institution of SCD-specific pain management protocols to combat structural racism and reduce time to opioid administration. The investigators' long-term goal is to improve the care and health outcomes of children with acute painful vaso-occlusive crisis treated in the emergency department. The overall aim of the investigators is to test a care pathway using multifaceted implementation strategies to increase guideline adherent care for children in the emergency department with acute painful vaso-occlusive crisis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05373771
Study type Interventional
Source Medical College of Wisconsin
Contact David Brousseau, MD, MS
Phone (302) 651-4000
Email david.brousseau@nemours.org
Status Recruiting
Phase N/A
Start date September 1, 2021
Completion date August 31, 2027
View Details
See also
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