Sickle Cell Anemia Clinical Trial
Official title:
Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea.Observational Retrospective Study.
Hydroxyurea was found to be a good treatment in adult patients with sickle cell anemia with significant decrease in the frequency of vaso-occlusive crises and other crises related to SCA. Several studies were published with relative short term follow up in pediatric and young adult age. The purpose of this study is to assess the long term follow up in a group of patients that initiated Hydroxyurea treatment in childhood.
Hydroxyurea was found to be a good treatment in adult patients with sickle cell anemia with
significant decrease in the frequency of vaso-occlusive crises and other crises related to
SCA. Several studies were published with relative short term follow up in pediatric and
young adult age. The purpose of this study is to assess the long term follow up in a group
of patients that initiated Hydroxyurea treatment in childhood.
A long term follow up will be recorded in a cohort of twenty SCA patients treated by
Hydroxyurea for a period between 5 to 12 years. The frequency of vaso-occlusive crises,
acute chest syndrome, blood transfusions, and hospitalization will be recorded
retrospectively. Also the mean hgb level and hgb F percentage will be summarized.
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Observational Model: Case-Only, Time Perspective: Retrospective
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