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Clinical Trial Summary

The hypothesis is that in sickle cell anaemia, nocturnal oxyhaemoglobin desaturation, is associated with low processing speed index, and this morbidity can be reduced with overnight auto Continuous Positive Airways Pressure and/or oxygen supplementation.


Clinical Trial Description

Intervention: Overnight auto Continuous Positive Airways Pressure (CPAP) with oxygen supplementation if mean overnight oxyhaemoglobin saturation is not >94% after 2 weeks of autoCPAP ;


Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind


Related Conditions & MeSH terms


NCT number NCT00415727
Study type Interventional
Source Institute of Child Health
Contact Fenella Kirkham, Dr
Email f.kirkham@ich.ucl.ac.uk
Status Recruiting
Phase Phase 2
Start date November 2006

See also
  Status Clinical Trial Phase
Completed NCT02844673 - Mobile-Directly Observed Therapy on Adherence to Hydroxyurea Phase 2