Clinical Trials Logo

Clinical Trial Summary

A consequence of chronic RV pacing is a process of electrical remodeling that alters myocardial repolarization to reflect the altered depolarization induced by the RV lead. When RV pacing is discontinued, the altered repolarization persists for several weeks. This phenomena is traditionally described as "T-wave memory" based upon the 12-lead ECG appearance of inverted T-Waves. The investigators are using the ECGI technique to produce three dimensional electroanatomical images of this phenomena in patients with dual chamber pacemakers. Echocardiography will also be used to image the mechanical effects of RV pacing and T-wave memory. The images will show the spatial distribution of altered repolarization and allow us to correlate any mechanical consequences of this phenomena that may exist.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT00785564
Study type Observational
Source Washington University School of Medicine
Contact
Status Completed
Phase
Start date November 2007
Completion date September 2011

See also
  Status Clinical Trial Phase
Completed NCT00286858 - Beluga - Clinical Observations of Automatic Algorithms for Cardiac Pacing
Active, not recruiting NCT00228241 - Left Ventricular Function and Remodelling During Permanent Pacing N/A
Completed NCT00180557 - Austria Study - Analysis of Difference Between Active and Passive Fixation Leads Phase 4
Not yet recruiting NCT04149886 - Cardiac Ganglionated Plexus Ablation Before Permanent Pacemaker Implantation in Patients With Sick Sinus Syndrome N/A
Completed NCT01609738 - Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum Phase 1/Phase 2
Recruiting NCT00161551 - Mode Evaluation in Sick Sinus Syndrome Trial (MODEST) Phase 4
Recruiting NCT00224341 - Arrhythmia Restart Prevention and RatE STabilization in Atrial Fibrillation Phase 4
Recruiting NCT05575557 - Pulmonary Artery Pressure and Right Heart Evaluation for Patients Requiring Physiological Pacing Treatment N/A
Recruiting NCT05186220 - Cardioneuroablation Versus Pacemaker Implantation for the Treatment of Symptomatic Sinus Node Dysfunction N/A
Completed NCT03843242 - Evaluation of Ventricular Pacing Suppression Algorithms in Dual Chamber Pacemaker N/A
Terminated NCT00475124 - Virtual Clinic Pacemaker Follow-up Phase 4
Recruiting NCT06288633 - Cardioneuroablation for Bradyarrhythmia N/A
Terminated NCT00236158 - The Danish Multicenter Randomised Study on AAI Versus DDD Pacing in Sick Sinus Syndrome Phase 2/Phase 3
Completed NCT00000561 - Mode Selection Trial in Sinus Node Dysfunction (MOST) Phase 3
Completed NCT02154750 - AV Delay Optimization vs. Intrinsic Conduction in Pacemaker Patients With Long PR Intervals N/A
Completed NCT02198781 - Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - Pilot
Recruiting NCT01477138 - RV Septal Versus Minimized RV Pacing in Sick Sinus Syndrome N/A
Terminated NCT01074749 - Optimal Sensing in Atrial Tachyarrhythmia's Study N/A
Completed NCT00161538 - Pacing of the Atria in Sick Sinus Syndrome Trial Preventive Strategies for Atrial Fibrillation Phase 4
Completed NCT00627328 - The Atrial High Rate Episodes in Pacemaker Patients N/A