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Imaging Cardiac Electrical Remodeling With Electrocardiogram Imaging (ECGI)

Sick Sinus Syndrome Clinical Trial

Official title:
Imaging Cardiac Electrical Remodeling With ECGI

Clinical Trial Summary

A consequence of chronic RV pacing is a process of electrical remodeling that alters myocardial repolarization to reflect the altered depolarization induced by the RV lead. When RV pacing is discontinued, the altered repolarization persists for several weeks. This phenomena is traditionally described as "T-wave memory" based upon the 12-lead ECG appearance of inverted T-Waves. The investigators are using the ECGI technique to produce three dimensional electroanatomical images of this phenomena in patients with dual chamber pacemakers. Echocardiography will also be used to image the mechanical effects of RV pacing and T-wave memory. The images will show the spatial distribution of altered repolarization and allow us to correlate any mechanical consequences of this phenomena that may exist.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00785564
Study type Observational
Source Washington University School of Medicine
Contact
Status Completed
Phase
Start date November 2007
Completion date September 2011
View Details
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