Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00829023
Other study ID # IRB 1232-008
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date June 2007
Est. completion date June 2008

Study information

Verified date February 2023
Source Northwestern University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of the present study was to examine the native bacteria around the shoulder and determine the efficacy of three different surgical skin-preparation solutions on the eradication of bacteria from the shoulder.


Description:

A prospective study was undertaken to evaluate 150 consecutive patients undergoing shoulder surgery at one institution. Each shoulder was prepared with one of three randomly selected solutions: ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol), DuraPrep (0.7% iodophor and 74% isopropyl alcohol), or povidone-iodine scrub and paint (0.75% iodine scrub, 1.0% iodine paint). Aerobic and anaerobic cultures were taken prior to skin preparation for the first twenty patients to determine the native bacteria around the shoulder and following skin preparation for all patients.


Recruitment information / eligibility

Status Completed
Enrollment 150
Est. completion date June 2008
Est. primary completion date June 2008
Accepts healthy volunteers No
Gender All
Age group 18 Years to 99 Years
Eligibility Inclusion Criteria: - shoulder surgery or any type Exclusion Criteria: - open wound, current infection, chronic immunosuppression

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
ChloraPrep Topical Product
surgical skin preparation solution 2% chlorhexidine gluconate and 70% isopropyl alcohol
Duraprep Surgical Topical Solution
surgical skin preparation solution 0.7% iodophor and 74% isopropyl alcohol
povidone-iodine scrub and paint
surgical skin preparation solution 0.75% iodine scrub and 1.0% iodine paint

Locations

Country Name City State
United States Northwestern Memorial Hospital Chicago Illinois

Sponsors (2)

Lead Sponsor Collaborator
Northwestern University CareFusion

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary positive culture results rate of positive cultures 7 days
Secondary infection rate of infection 6 months
See also
  Status Clinical Trial Phase
Withdrawn NCT04015284 - Intraoperative Pain and Quality of Surgical Block During Shoulder Surgery Assessed by NOL Index N/A
Completed NCT02284763 - Modeling the Effect of EtCO2 on Cerebral Oxygenation N/A
Completed NCT01229683 - Effects of Interscalene Brachial Plexus Nerve Blocks on the Hand and Forearm N/A
Recruiting NCT04209504 - Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
Terminated NCT00801138 - The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine Phase 2/Phase 3
Completed NCT05772533 - Serratus Anterior Plane Block Versus Pericapsular Nerve Group Block for Shoulder Surgery N/A
Not yet recruiting NCT00640380 - A Comparison Between Neurostimulation and Loss of Resistance for Cervical Paravertebral Blocks N/A
Recruiting NCT02125994 - Effect of 0.5% vs 0.375% Ropivacaine on Autonomous Nervous System N/A
Completed NCT05755802 - Shoulder Block Versus Pericapsular Nerve Group Block for Shoulder Surgery N/A
Completed NCT01185457 - Effect of Interscalene Block on Heart Rate Variability (HRV) N/A
Not yet recruiting NCT04397549 - Cervical Erector Spinae Block for Shoulder Surgery N/A
Completed NCT06396455 - Ultrasound Guided Suprascapular Nerve Block Versus ISB Block in Arthroscopic Shoulder Surgery N/A
Completed NCT02322242 - The Effects of Dexamethasone on Low Dose Interscalene Brachial Plexus Block Phase 4
Withdrawn NCT02435251 - Changes in Anthropometry Following Ambulatory Orthopaedic Surgery
Completed NCT01025102 - The Addition of Sufentanil Interscalene Block in Shoulder Surgery Phase 3
Completed NCT04714112 - Low-dose Intravenous Dexamethasone at Different Times as Adjunvants for Brachial Plexus Blocks Phase 4
Completed NCT04769570 - Effect of Interscalene and Suprascapular Nerve Block on Analgesia Consumption After Adhesive Capsulitis Surgery N/A
Completed NCT02074397 - Distant Extrafascial Injection vs Subfascial Injection for Interscalene Block: Acute Pain Outcomes and Rates of Complications N/A
Recruiting NCT03664284 - Does the Disinfection of the Subcutaneous Tissue Reduce the Contamination of the Operative Field by P. Acnes During Primary Shoulder Surgery? N/A
Enrolling by invitation NCT04673344 - Regeneten Patch vs Standard Care in Partial Thickness Rotator Cuff Repair N/A