Short Bowel Syndrome Clinical Trial
Official title:
Plasma Determination of Glucagon-like Peptide 2 as a Predictor of Recovery in Adults With Acute Intestinal Failure
Verified date | May 2008 |
Source | Imperial College London |
Contact | n/a |
Is FDA regulated | No |
Health authority | United Kingdom: Research Ethics Committee |
Study type | Observational |
The purpose of this study is to investigate the theory that the plasma level of Glucagon like peptide 2 (GLP-2) in patients with intestinal failure can predict their clinical recovery.
Status | Completed |
Enrollment | 30 |
Est. completion date | February 2008 |
Est. primary completion date | February 2008 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Men and woman, aged 18 years of age or older at the time of signing the informed consent form. - Referral to or direct admission to St. Mark's Hospital. - Acute intestinal failure resulting in TPN dependency as a result of major intestinal resection performed during admission to St. Mark's or at the referring hospital. Exclusion Criteria: - Inability to give consent or comply with the study. - Inability to take test meal (unable to be tested) - Severe renal impairment (interference with GLP-2 excretion) - Severe uncorrected anaemia (preventing additional blood-letting) - Uncontrolled diabetes mellitus (risk of hyperglycaemia) |
Observational Model: Case Control, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
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Imperial College London | CORE, St Mark's Hospital Foundation |
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