Echocardiographic and Laboratory Findings in Hemodynamic Monitoring of Shocked Patients

Shock Clinical Trial

Official title:

Comparison of Echocardiographic and Laboratory Findings in Hemodynamic Monitoring of Shocked Patients

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06343519
• Other study ID #: Shocked Patients Monitoring
• Status: Not yet recruiting
• Start date: May 2024
• Est. completion date: May 2026

Study information

• Verified date: March 2024
• Source: Assiut University
• Contact: Ahmed Osman
• Phone: +201002034265
• Email: dr_ahmed_atef_med[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Shocked patients require prompt and accurate assessment of their hemodynamic status to guide appropriate management. Echocardiography is a valuable tool for assessing cardiac function, while laboratory parameters such as mixed venous oxygen saturation and arterial blood lactate provide insights into tissue perfusion and oxygen metabolism. This study aims to compare echocardiographic findings, including cardiac index, speckle tracking parameters, and tissue Doppler indices, with laboratory findings in the evaluation of hemodynamic monitoring in shocked patients.

Description:

Shocked individuals necessitate expeditious and precise evaluation of their hemodynamic condition to direct appropriate treatment. The utilization of echocardiography is an invaluable method for appraising cardiac function, while the inclusion of laboratory parameters such as mixed venous oxygen saturation and arterial blood lactate offers valuable insights into tissue perfusion and oxygen metabolism. The primary objective of this study is to compare the echocardiographic discoveries, which encompass the assessment of cardiac index, speckle tracking parameters, and tissue Doppler indices, with the laboratory findings in the comprehensive assessment of hemodynamic monitoring in individuals experiencing shock. The purpose of this investigation is to delineate the correlation between echocardiographic and laboratory assessments in order to enhance our understanding of hemodynamic status in patients who are in a state of shock.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 60
• Est. completion date: May 2026
• Est. primary completion date: March 2026
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients diagnosed with shock based on clinical criteria (e.g., hypotension, signs of tissue hypoperfusion) requiring hemodynamic monitoring.
• Patients age > 18 year old.

Exclusion Criteria:

• Patients with pre-existing cardiac conditions affecting echocardiographic parameters, those receiving mechanical circulatory support.
• Patients with contraindications to echocardiography or blood sampling.

Related Conditions & MeSH terms

• Shock

Intervention

Device:
• Echocardiography
Measuring echocardiographic parameters (cardiac index, speckle tracking, tissue Doppler indices)

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (1)

Jardin F, Fourme T, Page B, Loubieres Y, Vieillard-Baron A, Beauchet A, Bourdarias JP. Persistent preload defect in severe sepsis despite fluid loading: A longitudinal echocardiographic study in patients with septic shock. Chest. 1999 Nov;116(5):1354-9. doi: 10.1378/chest.116.5.1354. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Shock Status After Fluid Therapy Based on Echocardiographic Assessment of Fluid Responsiveness	Change in shock status will be assessed 24 hours after initiation of fluid therapy by echocardiographic evaluation of cardiac index in liters per minute per square meter (L/min/m2).	24 hours