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NCT03932617 Clinical Trial

Correlation Between Changes in End-Tidal Carbon Dioxide and Stroke Volume Variation Detected by Electrical Cardiometry as A Predictor of Fluid Volume Responsiveness in Hemodynamically Unstable Patients in the Intensive Care

Shock Clinical Trial

Official title:
Correlation Between Changes in End-Tidal Carbon Dioxide and Stroke Volume Variation Detected by Electrical Cardiometry as A Predictor of Fluid Volume Responsiveness in Hemodynamically Unstable Patients in the Intensive Care

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03932617
Other study ID # 32880/01/19
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 1, 2019
Est. completion date January 31, 2021

Study information
Verified date February 2021
Source Tanta University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study will be conducted to assess the role of end-tidal carbon dioxide (PETCO2) monitoring to predict the fluid volume responsiveness in correlation with stroke volume variation detected by electrical cardiometry in patients with hemodynamic instability.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date January 31, 2021
Est. primary completion date January 1, 2021
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion criteria: - Patients who will be 18 years or older. - Patients on mechanical ventilation in the intensive care. - Patients developing hypotension (MABP) <65 mmHg. Exclusion Criteria: - Patients with organ/s failure at presentation. - Patients with deep venous thrombosis. - Patients with limb and pelvic fractures. - Pregnant patients

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• end tidal carbon dioxide by capnography
Moreover, since PETCO2 is mainly determined by tissue CO2 production (VCO2), alveolar ventilation and CO, when stable metabolic conditions are assumed and minute ventilation is kept constant, acute changes in PETCO2 have been shown to correlate strongly with changes in CO. Thus, PETCO2 has been suggested as a simple economic and noninvasive alternative for continuous assessment of CO in different shock states.

Locations
Country Name City State
Egypt Tanta University Hospitals Tanta ElGharbiaa

Sponsors (1)
Lead Sponsor Collaborator
Tanta University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Assessment of sensitivity and specificity of end tidal carbon dioxide monitoring in predicting fluid responsiveness in correlation with stoke volume variation detected by cardiometry 24 hour
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