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Tryptophan, Serotonin and Kynurenine in Septic Shock — TSK  

Shock, Septic Clinical Trial

Official title:
Tryptophan, Serotonin and Kynurenine in Septic Shock

Clinical Trial Summary

Septic shock is a major cause of mortality and morbidity worldwide. Serotonin (5-HT) is released by activated platelets into the circulation, and is mediator of endothelial dysfunction. 5-HT metabolism is known in immune system via specific 5-HT receptor, also in effects on the peripheral nervous system. Kinetic of 5-HT, tryptophan, kynurenine, MAO activity and IDO activity in human septic shock was never investigated.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00684736
Study type Observational
Source Central Hospital, Versailles
Contact
Status Completed
Phase N/A
Start date June 2004
Completion date April 2008
View Details
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